BAIT
EXO84
CG6095, DExo84, Dmel\CG6095, Exo84p, anon-WO0153538.55, onr, Dmel_CG6095
Exo84 ortholog (S. cerevisiae)
GO Process (14)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
- actomyosin contractile ring contraction [IMP]
- endocytic recycling [IMP]
- establishment or maintenance of cell polarity [IMP]
- maintenance of epithelial cell apical/basal polarity [IMP]
- meiosis I cytokinesis [IMP]
- meiosis II cytokinesis [IMP]
- meiotic spindle stabilization [IMP]
- neuron projection morphogenesis [IMP]
- neurotransmitter secretion [NAS]
- protein localization to plasma membrane [IMP]
- spermatid development [IMP]
- synaptic vesicle docking [NAS]
- synaptic vesicle targeting [NAS]
- vesicle-mediated transport [ISS]
Drosophila melanogaster
PREY
OSA
C819, CG7467, Dmel\CG7467, E(E2F)3C, anon-WO0118547.314, anon-WO0172774.126, eld, en(lz)4F/4H, l(3)00090, l(3)04539, l(3)j9C3, p300, Dmel_CG7467
CG7467 gene product from transcript CG7467-RE
GO Process (14)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- Wnt signaling pathway [IMP]
- imaginal disc-derived leg morphogenesis [IMP]
- imaginal disc-derived wing margin morphogenesis [IMP]
- imaginal disc-derived wing morphogenesis [IMP]
- imaginal disc-derived wing vein morphogenesis [IMP]
- negative regulation of neuroblast proliferation [IGI]
- neuroblast fate commitment [IMP]
- neurogenesis [IMP]
- photoreceptor cell differentiation [IMP]
- positive regulation of transcription, DNA-templated [IDA, IPI]
- regulation of epidermal growth factor receptor signaling pathway [IMP]
- regulation of transcription, DNA-templated [IDA, IMP]
- segment specification [IMP]
- wing disc dorsal/ventral pattern formation [IGI]
Gene Ontology Molecular Function
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Protein interaction mapping: a Drosophila case study.
The Drosophila (fruit fly) model system has been instrumental in our current understanding of human biology, development, and diseases. Here, we used a high-throughput yeast two-hybrid (Y2H)-based technology to screen 102 bait proteins from Drosophila melanogaster, most of them orthologous to human cancer-related and/or signaling proteins, against high-complexity fly cDNA libraries. More than 2300 protein-protein interactions (PPI) were identified, of ... [more]
Genome Res. Mar. 01, 2005; 15(3);376-84 [Pubmed: 15710747]
Throughput
- High Throughput
Additional Notes
- Predicted Biological Score:B
Curated By
- BioGRID