BAIT
N
1.1, 16-178, 16-55, Ax, CG3936, CT13012, Chp, Co, Dmel\CG3936, EG:140G11.1, EG:163A10.2, NECD, NICD, RICN, anon-EST:Liang-1.12, clone 1.12, dNotch, fa, l(1)3Cb, l(1)Ax, l(1)N, n[fah], nd, notch, shd, spl, swb, Dmel_CG3936
Notch
GO Process (111)
GO Function (4)
GO Component (15)
Gene Ontology Biological Process
- I-kappaB phosphorylation [IMP]
- Malpighian tubule tip cell differentiation [IMP]
- Notch signaling pathway [NAS]
- R1/R6 cell differentiation [IMP]
- R3/R4 cell fate commitment [NAS]
- R7 cell differentiation [IMP, TAS]
- R8 cell development [TAS]
- R8 cell differentiation [NAS]
- R8 cell fate commitment [TAS]
- actin filament organization [IMP]
- anesthesia-resistant memory [IMP]
- anterior/posterior pattern specification [TAS]
- asymmetric cell division [TAS]
- axon guidance [IMP]
- border follicle cell migration [IMP]
- cell adhesion [TAS]
- cell fate commitment [NAS]
- cell fate specification [NAS, TAS]
- chaeta development [IMP]
- chaeta morphogenesis [IMP]
- compound eye cone cell fate commitment [TAS]
- compound eye development [IMP, NAS, TAS]
- compound eye morphogenesis [IMP]
- compound eye retinal cell programmed cell death [TAS]
- crystal cell differentiation [IMP]
- determination of adult lifespan [IMP]
- dorsal appendage formation [IMP]
- dorsal closure [TAS]
- dorsal/ventral lineage restriction, imaginal disc [TAS]
- dorsal/ventral pattern formation, imaginal disc [TAS]
- ectoderm development [TAS]
- embryonic crystal cell differentiation [TAS]
- embryonic hemopoiesis [IMP]
- epithelial cell proliferation involved in Malpighian tubule morphogenesis [IMP]
- epithelial cell type specification, open tracheal system [IMP]
- epithelium development [IMP]
- establishment of imaginal disc-derived wing hair orientation [NAS]
- establishment of ommatidial planar polarity [NAS, TAS]
- eye-antennal disc development [IMP]
- foregut morphogenesis [IMP]
- formation of a compartment boundary [IMP]
- germ-line stem cell maintenance [IMP]
- germarium-derived egg chamber formation [IMP, TAS]
- germarium-derived female germ-line cyst encapsulation [TAS]
- germarium-derived female germ-line cyst formation [IMP]
- glial cell differentiation [IMP]
- glial cell fate determination [IMP]
- glial cell migration [IMP]
- hemocyte proliferation [IMP]
- heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [IDA, IMP]
- imaginal disc growth [TAS]
- imaginal disc pattern formation [TAS]
- imaginal disc-derived leg joint morphogenesis [IMP]
- imaginal disc-derived leg segmentation [IMP]
- imaginal disc-derived male genitalia morphogenesis [IMP]
- imaginal disc-derived wing margin morphogenesis [IMP]
- imaginal disc-derived wing morphogenesis [IMP, NAS]
- imaginal disc-derived wing vein specification [IMP]
- intestinal stem cell homeostasis [IMP]
- lamellocyte differentiation [IMP]
- larval lymph gland hemopoiesis [IMP]
- lateral inhibition [IMP, NAS, TAS]
- leg disc morphogenesis [TAS]
- long-term memory [IGI, IMP]
- lymph gland crystal cell differentiation [TAS]
- lymph gland development [IMP]
- mesoderm development [IMP]
- morphogenesis of follicular epithelium [NAS]
- motor neuron axon guidance [IMP]
- muscle cell fate determination [IMP]
- negative regulation of JNK cascade [NAS]
- negative regulation of compound eye photoreceptor development [IMP]
- negative regulation of fusion cell fate specification [TAS]
- negative regulation of gene expression [IMP]
- negative regulation of neurogenesis [IMP]
- negative regulation of terminal cell fate specification, open tracheal system [TAS]
- negative regulation of transcription from RNA polymerase II promoter [TAS]
- neuroblast fate determination [IDA]
- neurological system process [IMP]
- neuron development [IMP]
- oocyte anterior/posterior axis specification [TAS]
- oocyte localization involved in germarium-derived egg chamber formation [IMP]
- oogenesis [IMP]
- open tracheal system development [TAS]
- ovarian follicle cell development [IMP, TAS]
- ovarian follicle cell migration [IMP]
- ovarian follicle cell stalk formation [IMP, TAS]
- peripheral nervous system development [IMP, TAS]
- positive regulation of G1/S transition of mitotic cell cycle [IMP]
- positive regulation of Notch signaling pathway [IMP]
- positive regulation of cell proliferation [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of R8 cell spacing in compound eye [NAS]
- regulation of cardioblast cell fate specification [IMP]
- regulation of cell differentiation [IMP]
- regulation of crystal cell differentiation [TAS]
- regulation of filopodium assembly [IMP]
- regulation of growth [IGI, IMP]
- regulation of mitotic cell cycle [TAS]
- regulation of neurogenesis [IMP]
- response to symbiont [IMP]
- retinal cell programmed cell death [TAS]
- second mitotic wave involved in compound eye morphogenesis [IMP, NAS]
- sensory organ development [IMP]
- sensory organ precursor cell fate determination [IMP]
- skeletal muscle tissue development [IMP]
- stem cell differentiation [IMP]
- ventral cord development [NAS]
- wing disc dorsal/ventral pattern formation [IMP]
- wing disc pattern formation [IMP]
- wing disc proximal/distal pattern formation [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- adherens junction [IDA]
- cell surface [IDA]
- cytoplasm [IDA]
- cytoplasmic vesicle [IDA]
- endocytic vesicle [IDA]
- endosome [IDA]
- integral component of membrane [TAS]
- integral component of plasma membrane [NAS]
- intracellular [IDA, NAS]
- late endosome [IDA]
- lysosome [IDA]
- nucleus [IDA, NAS, TAS]
- plasma membrane [IDA]
- protein complex [IPI]
- subapical complex [IDA]
Drosophila melanogaster
PREY
CG43333
BG:DS01523.2, CG15291, CG32972, Dmel\CG43333, Dmel_CG32972, Dmel_CG43333
CG43333 gene product from transcript CG43333-RA
GO Process (0)
GO Function (0)
GO Component (0)
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Protein interaction mapping: a Drosophila case study.
The Drosophila (fruit fly) model system has been instrumental in our current understanding of human biology, development, and diseases. Here, we used a high-throughput yeast two-hybrid (Y2H)-based technology to screen 102 bait proteins from Drosophila melanogaster, most of them orthologous to human cancer-related and/or signaling proteins, against high-complexity fly cDNA libraries. More than 2300 protein-protein interactions (PPI) were identified, of ... [more]
Genome Res. Mar. 01, 2005; 15(3);376-84 [Pubmed: 15710747]
Throughput
- High Throughput
Additional Notes
- Predicted Biological Score:D
Curated By
- BioGRID