BAIT
MER
BG01543, CG14228, D-Mer, Dmel\CG14228, Dmerlin, EMR2, NF2, Dmel_CG14228
Merlin
GO Process (28)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
- axis specification [IMP]
- cell cycle arrest [IGI]
- cell-cell signaling [IEP]
- compound eye morphogenesis [IGI]
- compound eye photoreceptor cell differentiation [IGI]
- decapentaplegic signaling pathway [IGI]
- endocytic recycling [IGI]
- endocytosis [IEP]
- hippo signaling [IGI]
- imaginal disc-derived wing morphogenesis [IMP]
- male meiosis cytokinesis [IMP]
- meiotic chromosome separation [IMP]
- negative regulation of cell proliferation [IGI, IMP]
- negative regulation of glial cell proliferation [IMP]
- negative regulation of organ growth [IGI, IMP]
- olfactory behavior [IMP]
- pole plasm mRNA localization [IMP]
- positive regulation of phosphorylation [IGI]
- positive regulation of protein phosphorylation [IDA]
- protein localization to plasma membrane [IMP]
- regulation of apoptotic process [IGI]
- regulation of cell differentiation [IGI]
- regulation of cell growth [IEP]
- regulation of cell proliferation [IMP]
- regulation of compound eye retinal cell programmed cell death [IMP]
- regulation of signal transduction [IGI]
- sperm individualization [IMP]
- spermatogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Drosophila melanogaster
PREY
CG42699
CG15770, CG4064, Dmel\CG42699, Dmel_CG15770, Dmel_CG4064, Dmel_CG42699
CG42699 gene product from transcript CG42699-RC
GO Process (0)
GO Function (0)
GO Component (0)
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Protein interaction mapping: a Drosophila case study.
The Drosophila (fruit fly) model system has been instrumental in our current understanding of human biology, development, and diseases. Here, we used a high-throughput yeast two-hybrid (Y2H)-based technology to screen 102 bait proteins from Drosophila melanogaster, most of them orthologous to human cancer-related and/or signaling proteins, against high-complexity fly cDNA libraries. More than 2300 protein-protein interactions (PPI) were identified, of ... [more]
Genome Res. Mar. 01, 2005; 15(3);376-84 [Pubmed: 15710747]
Throughput
- High Throughput
Additional Notes
- Predicted Biological Score:D
Curated By
- BioGRID