BAIT
SPI
CG10334, CT29014, Dmel\CG10334, EP(2)2378, Spitz, anon-WO0118547.158, l(2)01068, l(2)37Fa, l(2)s3547, s-spi, sSpi, Dmel_CG10334
spitz
GO Process (25)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
- G2/M transition of mitotic cell cycle [NAS]
- R8 cell-mediated photoreceptor organization [NAS]
- behavioral response to ethanol [IMP]
- border follicle cell migration [IMP]
- branched duct epithelial cell fate determination, open tracheal system [TAS]
- determination of genital disc primordium [IMP]
- epidermal growth factor receptor signaling pathway [NAS, TAS]
- epithelial cell proliferation involved in Malpighian tubule morphogenesis [IMP]
- heart process [IMP]
- imaginal disc-derived wing morphogenesis [IMP]
- negative regulation of apoptotic process [IMP, NAS]
- negative regulation of compound eye retinal cell programmed cell death [NAS]
- neurogenesis [IMP]
- oenocyte development [IGI, IMP]
- olfactory learning [IMP]
- open tracheal system development [TAS]
- peripheral nervous system development [IMP]
- positive regulation of cell proliferation [IMP]
- positive regulation of epidermal growth factor receptor signaling pathway [NAS]
- positive regulation of neurogenesis [IMP]
- salivary gland boundary specification [NAS]
- second mitotic wave involved in compound eye morphogenesis [NAS]
- spiracle morphogenesis, open tracheal system [IMP]
- stem cell fate commitment [IMP]
- stomatogastric nervous system development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Drosophila melanogaster
PREY
HNF4
CG9310, DmHNF4, Dmel\CG9310, HNF-4, HNF-4(D), HNF4alpha, Hnf-4h, NR2A4, dHNF-4, dHNF4, Dmel_CG9310
Hepatocyte nuclear factor 4
GO Process (5)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Protein interaction mapping: a Drosophila case study.
The Drosophila (fruit fly) model system has been instrumental in our current understanding of human biology, development, and diseases. Here, we used a high-throughput yeast two-hybrid (Y2H)-based technology to screen 102 bait proteins from Drosophila melanogaster, most of them orthologous to human cancer-related and/or signaling proteins, against high-complexity fly cDNA libraries. More than 2300 protein-protein interactions (PPI) were identified, of ... [more]
Genome Res. Mar. 01, 2005; 15(3);376-84 [Pubmed: 15710747]
Throughput
- High Throughput
Additional Notes
- Predicted Biological Score:D
Curated By
- BioGRID