BAIT
CG17985
Dmel\CG17985, Dmel_CG17985
CG17985 gene product from transcript CG17985-RA
GO Process (0)
GO Function (0)
GO Component (0)
Drosophila melanogaster
PREY
PGRP-LC
(PGRP)-LC, CG4432, Dm PGRP-LC, Dmel\CG4432, PGRP-LCa, PGRP-LCx, PGRPLC, ird7, tot, Dmel_CG4432
Peptidoglycan recognition protein LC
GO Process (16)
GO Function (8)
GO Component (4)
Gene Ontology Biological Process
- antibacterial humoral response [IDA, IMP]
- antimicrobial humoral response [IMP]
- defense response [NAS]
- defense response to Gram-negative bacterium [IDA, IMP, TAS]
- defense response to virus [IMP]
- detection of bacterium [NAS]
- immune response [IMP, ISS]
- innate immune response [NAS, TAS]
- peptidoglycan catabolic process [IKR]
- peptidoglycan recognition protein signaling pathway [IDA, IGI, IMP]
- phagocytosis [TAS]
- positive regulation of antibacterial peptide biosynthetic process [IMP, TAS]
- positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [IMP, NAS]
- regulation of humoral immune response [IMP]
- regulation of melanization defense response [IMP]
- response to bacterium [IMP]
Gene Ontology Molecular Function- N-acetylmuramoyl-L-alanine amidase activity [IKR]
- lipopolysaccharide receptor activity [IMP]
- peptidoglycan binding [IDA, ISS, NAS, TAS]
- peptidoglycan peptide transporter activity [IMP]
- peptidoglycan receptor activity [IMP, NAS, TAS]
- protein binding [IPI]
- protein dimerization activity [IDA, NAS]
- signaling pattern recognition receptor activity [TAS]
- N-acetylmuramoyl-L-alanine amidase activity [IKR]
- lipopolysaccharide receptor activity [IMP]
- peptidoglycan binding [IDA, ISS, NAS, TAS]
- peptidoglycan peptide transporter activity [IMP]
- peptidoglycan receptor activity [IMP, NAS, TAS]
- protein binding [IPI]
- protein dimerization activity [IDA, NAS]
- signaling pattern recognition receptor activity [TAS]
Gene Ontology Cellular Component
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]
Throughput
- High Throughput
Curated By
- BioGRID