SPN-B
Gene Ontology Biological Process
- DNA recombination [ISS]
- DNA repair [ISS, NAS]
- chromosome condensation [TAS]
- double-strand break repair [TAS]
- germarium-derived oocyte fate determination [IGI]
- intracellular mRNA localization [IMP, TAS]
- karyosome formation [IMP]
- meiotic nuclear division [TAS]
- oocyte differentiation [NAS]
- oogenesis [IGI, TAS]
- polarity specification of anterior/posterior axis [IMP]
- polarity specification of dorsal/ventral axis [IMP]
- reciprocal meiotic recombination [TAS]
- regulation of translation [TAS]
Gene Ontology Molecular Function
RECQ5
Gene Ontology Biological Process
Gene Ontology Molecular Function
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Protein interaction mapping: a Drosophila case study.
The Drosophila (fruit fly) model system has been instrumental in our current understanding of human biology, development, and diseases. Here, we used a high-throughput yeast two-hybrid (Y2H)-based technology to screen 102 bait proteins from Drosophila melanogaster, most of them orthologous to human cancer-related and/or signaling proteins, against high-complexity fly cDNA libraries. More than 2300 protein-protein interactions (PPI) were identified, of ... [more]
Throughput
- High Throughput
Additional Notes
- Predicted Biological Score:D
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
SPN-B RECQ5 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |
Curated By
- BioGRID