BAIT
FYCO1
CATC2, CTRCT18, RUFY3, ZFYVE7
FYVE and coiled-coil domain containing 1
GO Process (1)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
KIF5B
HEL-S-61, KINH, KNS, KNS1, UKHC
kinesin family member 5B
GO Process (10)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- axon guidance [IBA]
- cellular protein metabolic process [TAS]
- cytoskeleton-dependent intracellular transport [IBA]
- microtubule-based movement [IBA]
- positive regulation of establishment of protein localization to plasma membrane [IDA]
- positive regulation of potassium ion transport [IDA]
- regulation of membrane potential [IDA]
- stress granule disassembly [ISS]
- vesicle transport along microtubule [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Network organization of the human autophagy system.
Autophagy, the process by which proteins and organelles are sequestered in autophagosomal vesicles and delivered to the lysosome/vacuole for degradation, provides a primary route for turnover of stable and defective cellular proteins. Defects in this system are linked with numerous human diseases. Although conserved protein kinase, lipid kinase and ubiquitin-like protein conjugation subnetworks controlling autophagosome formation and cargo recruitment have ... [more]
Nature Jul. 01, 2010; 466(7302);68-76 [Pubmed: 20562859]
Throughput
- High Throughput
Ontology Terms
- cell line: hek-293 cell (BTO:0000007)
Additional Notes
- Exogenous expression of bait
Curated By
- BioGRID