BAIT
MAP1LC3A
ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3, RP11-346K17.1
microtubule-associated protein 1 light chain 3 alpha
GO Process (5)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RAB3GAP2
RAB3-GAP150, RAB3GAP150, SPG69, WARBM2, p150, RP11-568G11.1
RAB3 GTPase activating protein subunit 2 (non-catalytic)
GO Process (7)
GO Function (5)
GO Component (3)
Gene Ontology Biological Process
- establishment of protein localization to endoplasmic reticulum membrane [IMP]
- intracellular protein transport [TAS]
- positive regulation of GTPase activity [TAS]
- positive regulation of Rab GTPase activity [IMP]
- positive regulation of catalytic activity [TAS]
- positive regulation of endoplasmic reticulum tubular network organization [IMP]
- regulation of GTPase activity [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Network organization of the human autophagy system.
Autophagy, the process by which proteins and organelles are sequestered in autophagosomal vesicles and delivered to the lysosome/vacuole for degradation, provides a primary route for turnover of stable and defective cellular proteins. Defects in this system are linked with numerous human diseases. Although conserved protein kinase, lipid kinase and ubiquitin-like protein conjugation subnetworks controlling autophagosome formation and cargo recruitment have ... [more]
Nature Jul. 01, 2010; 466(7302);68-76 [Pubmed: 20562859]
Throughput
- High Throughput
Ontology Terms
- cell line: hek-293 cell (BTO:0000007)
Additional Notes
- Exogenous expression of bait
Curated By
- BioGRID