BAIT
UBA5
THIFP1, UBE1DC1
ubiquitin-like modifier activating enzyme 5
GO Process (3)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
HSD17B4
DBP, MFE-2, MPF-2, PRLTS1, SDR8C1
hydroxysteroid (17-beta) dehydrogenase 4
GO Process (15)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- alpha-linolenic acid metabolic process [TAS]
- androgen metabolic process [IDA]
- bile acid biosynthetic process [TAS]
- bile acid metabolic process [TAS]
- cellular lipid metabolic process [TAS]
- estrogen metabolic process [IDA]
- fatty acid beta-oxidation [IDA]
- fatty acid beta-oxidation using acyl-CoA oxidase [TAS]
- medium-chain fatty-acyl-CoA metabolic process [IDA]
- metabolic process [IDA]
- osteoblast differentiation [IDA]
- oxidation-reduction process [IDA, IMP]
- small molecule metabolic process [TAS]
- unsaturated fatty acid metabolic process [TAS]
- very long-chain fatty-acyl-CoA metabolic process [IDA]
Gene Ontology Molecular Function- 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [IDA]
- 3-hydroxyacyl-CoA dehydrogenase activity [IDA, IMP, TAS]
- 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [TAS]
- long-chain-enoyl-CoA hydratase activity [IDA, TAS]
- protein homodimerization activity [IDA]
- receptor binding [IPI]
- 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [IDA]
- 3-hydroxyacyl-CoA dehydrogenase activity [IDA, IMP, TAS]
- 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [TAS]
- long-chain-enoyl-CoA hydratase activity [IDA, TAS]
- protein homodimerization activity [IDA]
- receptor binding [IPI]
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Network organization of the human autophagy system.
Autophagy, the process by which proteins and organelles are sequestered in autophagosomal vesicles and delivered to the lysosome/vacuole for degradation, provides a primary route for turnover of stable and defective cellular proteins. Defects in this system are linked with numerous human diseases. Although conserved protein kinase, lipid kinase and ubiquitin-like protein conjugation subnetworks controlling autophagosome formation and cargo recruitment have ... [more]
Nature Jul. 01, 2010; 466(7302);68-76 [Pubmed: 20562859]
Throughput
- High Throughput
Ontology Terms
- cell line: hek-293 cell (BTO:0000007)
Additional Notes
- Exogenous expression of bait
Curated By
- BioGRID