BAIT
UBA5
THIFP1, UBE1DC1
ubiquitin-like modifier activating enzyme 5
GO Process (3)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
GSTO1
GSTO 1-1, GSTTLp28, HEL-S-21, P28, SPG-R, RP11-99N20.1
glutathione S-transferase omega 1
GO Process (11)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- L-ascorbic acid metabolic process [IDA]
- cellular response to arsenic-containing substance [IDA]
- glutathione derivative biosynthetic process [TAS]
- negative regulation of ryanodine-sensitive calcium-release channel activity [IDA]
- positive regulation of ryanodine-sensitive calcium-release channel activity [IDA]
- positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [IC]
- regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [IC]
- regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [IDA]
- small molecule metabolic process [TAS]
- xenobiotic catabolic process [IDA]
- xenobiotic metabolic process [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Network organization of the human autophagy system.
Autophagy, the process by which proteins and organelles are sequestered in autophagosomal vesicles and delivered to the lysosome/vacuole for degradation, provides a primary route for turnover of stable and defective cellular proteins. Defects in this system are linked with numerous human diseases. Although conserved protein kinase, lipid kinase and ubiquitin-like protein conjugation subnetworks controlling autophagosome formation and cargo recruitment have ... [more]
Nature Jul. 01, 2010; 466(7302);68-76 [Pubmed: 20562859]
Throughput
- High Throughput
Ontology Terms
- hek-293 cell (BTO:0000007)
Additional Notes
- Exogenous expression of bait
Curated By
- BioGRID