SWI5
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
MUS81
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Phenotypic Enhancement
A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.
Publication
Crossover invariance determined by partner choice for meiotic DNA break repair.
Crossovers between meiotic homologs are crucial for their proper segregation, and crossover number and position are carefully controlled. Crossover homeostasis in budding yeast maintains crossovers at the expense of noncrossovers when double-strand DNA break (DSB) frequency is reduced. The mechanism of maintaining constant crossover levels in other species has been unknown. Here we investigate in fission yeast a different aspect ... [more]
Throughput
- Low Throughput
Ontology Terms
- phenotype: meiotic recombination (APO:0000040)
Additional Notes
- double mutants show increased loss of double holiday junctures compared to single mutants
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
SWI5 MUS81 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 247969 |
Curated By
- BioGRID