ACP2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
FIM1
Gene Ontology Biological Process
- actin cortical patch localization [IMP]
- actin crosslink formation [IPI]
- actin cytoskeleton organization [IGI]
- actin filament bundle assembly [IMP]
- ascospore formation [IMP]
- establishment or maintenance of cell polarity regulating cell shape [IMP]
- mitotic actomyosin contractile ring assembly [IMP]
- mitotic cytokinesis [IGI]
- negative regulation of actin filament depolymerization [IMP]
- regulation of cell shape [IGI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Synthetic Growth Defect
A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell.
Publication
Actin-capping protein is involved in controlling organization of actin cytoskeleton together with ADF/cofilin, profilin and F-actin crosslinking proteins in fission yeast.
Actin-capping protein (CP) is a heterodimeric protein which is expressed in various eukaryotic cells. CP binds to the barbed end of the actin filaments in vitro and inhibits both the association and dissociation of actin monomers at this end. However, the cellular role of CP has not been uncovered. Here we investigated the function of CP in fission yeast cells. ... [more]
Throughput
- Low Throughput
Ontology Terms
- phenotype: vegetative growth (APO:0000106)
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ACP2 FIM1 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 670060 |
Curated By
- BioGRID