BAIT

ART1

SPBC19G7.08c
arrestin family protein Art1
GO Process (0)
GO Function (1)
GO Component (1)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Schizosaccharomyces pombe (972h)
PREY

SPN1

SPAC4F10.11
septin Spn1
GO Process (2)
GO Function (1)
GO Component (5)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Schizosaccharomyces pombe (972h)

Synthetic Lethality

A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.

Publication

Cooperation Between the Septins and the Actomyosin Ring and Role of a Cell-integrity Pathway During Cell Division in Fission Yeast.

Wu JQ, Ye Y, Wang N, Pollard TD, Pringle JR

A major question about cytokinesis is the role of the septin proteins, which localize to the division site in all animal and fungal cells but are essential for cytokinesis only in some cell types. For example, in Schizosaccharomyces pombe, four septins localize to the division site, but deletion of the four genes produces only a modest delay in cell separation. ... [more]

Unknown Aug. 25, 2010; 0(0); [Pubmed: 20739711]

Throughput

  • Low Throughput

Ontology Terms

  • phenotype: cell death (APO:0000312)
  • phenotype: inviable (APO:0000112)

Additional Notes

  • double mutants show aberrant cell lysis

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
SPN1 ART1
Synthetic Growth Defect
Synthetic Growth Defect

A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell.

Low-BioGRID
452579

Curated By

  • BioGRID