BAIT
PLEKHA5
PEPP-2, PEPP2
pleckstrin homology domain containing, family A member 5
GO Process (0)
GO Function (2)
GO Component (1)
Gene Ontology Molecular Function
Homo sapiens
PREY
DES
CSM1, CSM2, LGMD2R
desmin
GO Process (4)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human MAP kinase interactome.
Mitogen-activated protein kinase (MAPK) pathways form the backbone of signal transduction in the mammalian cell. Here we applied a systematic experimental and computational approach to map 2,269 interactions between human MAPK-related proteins and other cellular machinery and to assemble these data into functional modules. Multiple lines of evidence including conservation with yeast supported a core network of 641 interactions. Using ... [more]
Nat. Methods Oct. 01, 2010; 7(10);801-5 [Pubmed: 20936779]
Throughput
- High Throughput
Curated By
- BioGRID