BAIT
TOLLIP
IL-1RAcPIP
toll interacting protein
GO Process (8)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TBX3
TBX3-ISO, UMS, XHL
T-box 3
GO Process (21)
GO Function (6)
GO Component (1)
Gene Ontology Biological Process
- anterior/posterior axis specification, embryo [IMP]
- cell aging [IDA]
- cellular senescence [IDA]
- embryonic digit morphogenesis [IMP]
- embryonic forelimb morphogenesis [IMP]
- female genitalia development [IMP]
- follicle-stimulating hormone secretion [IMP]
- forelimb morphogenesis [IDA]
- luteinizing hormone secretion [IMP]
- male genitalia development [IMP]
- mammary gland development [IMP]
- mesoderm morphogenesis [IMP]
- negative regulation of apoptotic process [IDA]
- negative regulation of myoblast differentiation [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- organ morphogenesis [IDA]
- positive regulation of cell cycle [IDA]
- positive regulation of cell proliferation [IDA]
- regulation of transcription from RNA polymerase II promoter [TAS]
- skeletal system development [IMP]
Gene Ontology Molecular Function- RNA polymerase II activating transcription factor binding [ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II transcription factor binding [ISS]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- RNA polymerase II activating transcription factor binding [ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II transcription factor binding [ISS]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human MAP kinase interactome.
Mitogen-activated protein kinase (MAPK) pathways form the backbone of signal transduction in the mammalian cell. Here we applied a systematic experimental and computational approach to map 2,269 interactions between human MAPK-related proteins and other cellular machinery and to assemble these data into functional modules. Multiple lines of evidence including conservation with yeast supported a core network of 641 interactions. Using ... [more]
Nat. Methods Oct. 01, 2010; 7(10);801-5 [Pubmed: 20936779]
Throughput
- High Throughput
Curated By
- BioGRID