BAIT
WNK1
HSAN2, HSN2, KDP, PPP1R167, PRKWNK1, PSK, p65
WNK lysine deficient protein kinase 1
GO Process (7)
GO Function (5)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
TSC22D1
Ptg-2, TGFB1I4, TSC22, RP11-269C23.2
TSC22 domain family, member 1
GO Process (1)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human MAP kinase interactome.
Mitogen-activated protein kinase (MAPK) pathways form the backbone of signal transduction in the mammalian cell. Here we applied a systematic experimental and computational approach to map 2,269 interactions between human MAPK-related proteins and other cellular machinery and to assemble these data into functional modules. Multiple lines of evidence including conservation with yeast supported a core network of 641 interactions. Using ... [more]
Nat. Methods Oct. 01, 2010; 7(10);801-5 [Pubmed: 20936779]
Throughput
- High Throughput
Curated By
- BioGRID