BAIT
MAPK10
JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK, RP13-514E23.1
mitogen-activated protein kinase 10
GO Process (20)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- JNK cascade [ISS, TAS]
- JUN phosphorylation [ISS, TAS]
- MyD88-dependent toll-like receptor signaling pathway [TAS]
- MyD88-independent toll-like receptor signaling pathway [TAS]
- TRIF-dependent toll-like receptor signaling pathway [TAS]
- activation of MAPK activity [TAS]
- innate immune response [TAS]
- regulation of sequence-specific DNA binding transcription factor activity [TAS]
- signal transduction [TAS]
- stress-activated MAPK cascade [TAS]
- toll-like receptor 10 signaling pathway [TAS]
- toll-like receptor 2 signaling pathway [TAS]
- toll-like receptor 3 signaling pathway [TAS]
- toll-like receptor 4 signaling pathway [TAS]
- toll-like receptor 5 signaling pathway [TAS]
- toll-like receptor 9 signaling pathway [TAS]
- toll-like receptor TLR1:TLR2 signaling pathway [TAS]
- toll-like receptor TLR6:TLR2 signaling pathway [TAS]
- toll-like receptor signaling pathway [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CEP290
3H11Ag, BBS14, CT87, JBTS5, LCA10, MKS4, NPHP6, POC3, SLSN6, rd16
centrosomal protein 290kDa
GO Process (12)
GO Function (2)
GO Component (10)
Gene Ontology Biological Process
- G2/M transition of mitotic cell cycle [TAS]
- cilium assembly [ISS]
- cilium morphogenesis [ISS]
- eye photoreceptor cell development [ISS]
- hindbrain development [ISS]
- mitotic cell cycle [TAS]
- otic vesicle formation [ISS]
- positive regulation of intracellular protein transport [IMP]
- positive regulation of transcription, DNA-templated [IDA]
- pronephros development [ISS]
- protein transport [ISS]
- regulation of establishment of protein localization [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human MAP kinase interactome.
Mitogen-activated protein kinase (MAPK) pathways form the backbone of signal transduction in the mammalian cell. Here we applied a systematic experimental and computational approach to map 2,269 interactions between human MAPK-related proteins and other cellular machinery and to assemble these data into functional modules. Multiple lines of evidence including conservation with yeast supported a core network of 641 interactions. Using ... [more]
Nat. Methods Oct. 01, 2010; 7(10);801-5 [Pubmed: 20936779]
Throughput
- High Throughput
Curated By
- BioGRID