BAIT
MAPK14
CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA, RP1-179N16.5
mitogen-activated protein kinase 14
GO Process (46)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
- 3'-UTR-mediated mRNA stabilization [TAS]
- MyD88-dependent toll-like receptor signaling pathway [TAS]
- MyD88-independent toll-like receptor signaling pathway [TAS]
- RNA metabolic process [TAS]
- Ras protein signal transduction [TAS]
- TRIF-dependent toll-like receptor signaling pathway [TAS]
- activation of MAPK activity [TAS]
- blood coagulation [TAS]
- cell surface receptor signaling pathway [TAS]
- cellular component movement [TAS]
- cellular response to ionizing radiation [IMP]
- cellular response to lipopolysaccharide [IDA]
- cellular response to vascular endothelial growth factor stimulus [IMP]
- chemotaxis [TAS]
- gene expression [TAS]
- innate immune response [TAS]
- intracellular signal transduction [IDA]
- mRNA metabolic process [TAS]
- muscle cell differentiation [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- osteoclast differentiation [ISS]
- p38MAPK cascade [ISS]
- peptidyl-serine phosphorylation [ISS]
- platelet activation [TAS]
- positive regulation of blood vessel endothelial cell migration [IMP]
- positive regulation of muscle cell differentiation [TAS]
- positive regulation of myoblast differentiation [ISS]
- positive regulation of myoblast fusion [ISS]
- positive regulation of myotube differentiation [ISS]
- positive regulation of reactive oxygen species metabolic process [IMP]
- regulation of sequence-specific DNA binding transcription factor activity [TAS]
- regulation of transcription from RNA polymerase II promoter [ISS]
- signal transduction [TAS]
- signal transduction in response to DNA damage [IMP]
- stress-activated MAPK cascade [TAS]
- stress-induced premature senescence [IMP]
- toll-like receptor 10 signaling pathway [TAS]
- toll-like receptor 2 signaling pathway [TAS]
- toll-like receptor 3 signaling pathway [TAS]
- toll-like receptor 4 signaling pathway [TAS]
- toll-like receptor 5 signaling pathway [TAS]
- toll-like receptor 9 signaling pathway [TAS]
- toll-like receptor TLR1:TLR2 signaling pathway [TAS]
- toll-like receptor TLR6:TLR2 signaling pathway [TAS]
- toll-like receptor signaling pathway [TAS]
- vascular endothelial growth factor receptor signaling pathway [IMP]
Gene Ontology Molecular Function
Homo sapiens
PREY
MOB3B
C9orf35, MOB1D, MOBKL2B
MOB kinase activator 3B
GO Process (0)
GO Function (1)
GO Component (0)
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human MAP kinase interactome.
Mitogen-activated protein kinase (MAPK) pathways form the backbone of signal transduction in the mammalian cell. Here we applied a systematic experimental and computational approach to map 2,269 interactions between human MAPK-related proteins and other cellular machinery and to assemble these data into functional modules. Multiple lines of evidence including conservation with yeast supported a core network of 641 interactions. Using ... [more]
Nat. Methods Oct. 01, 2010; 7(10);801-5 [Pubmed: 20936779]
Throughput
- High Throughput
Curated By
- BioGRID