BAIT
BANF1
BAF, BCRP1, D14S1460, NGPS
barrier to autointegration factor 1
GO Process (6)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
APTX
AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT, RP11-562M8.1
aprataxin
GO Process (8)
GO Function (10)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function- DNA 5'-adenosine monophosphate hydrolase activity [IDA]
- chromatin binding [IDA]
- damaged DNA binding [IDA]
- double-stranded DNA binding [IDA]
- double-stranded RNA binding [IDA]
- phosphoglycolate phosphatase activity [IDA]
- phosphoprotein binding [IPI]
- polynucleotide 3'-phosphatase activity [IDA]
- protein N-terminus binding [IPI]
- protein binding [IPI]
- DNA 5'-adenosine monophosphate hydrolase activity [IDA]
- chromatin binding [IDA]
- damaged DNA binding [IDA]
- double-stranded DNA binding [IDA]
- double-stranded RNA binding [IDA]
- phosphoglycolate phosphatase activity [IDA]
- phosphoprotein binding [IPI]
- polynucleotide 3'-phosphatase activity [IDA]
- protein N-terminus binding [IPI]
- protein binding [IPI]
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Barrier-to-autointegration factor proteome reveals chromatin-regulatory partners.
Nuclear lamin filaments and associated proteins form a nucleoskeletal ("lamina") network required for transcription, replication, chromatin organization and epigenetic regulation in metazoans. Lamina defects cause human disease ("laminopathies") and are linked to aging. Barrier-to-autointegration factor (BAF) is a mobile and essential component of the nuclear lamina that binds directly to histones, lamins and LEM-domain proteins, including the inner nuclear membrane ... [more]
PLoS ONE Sep. 18, 2009; 4(9);e7050 [Pubmed: 19759913]
Throughput
- Low Throughput
Curated By
- BioGRID