ZFPM1
Gene Ontology Biological Process
- atrial septum morphogenesis [IMP]
- atrioventricular valve morphogenesis [IMP]
- cardiac muscle tissue morphogenesis [IMP]
- definitive erythrocyte differentiation [IMP]
- embryonic hemopoiesis [IMP]
- erythrocyte differentiation [IGI, IMP]
- granulocyte differentiation [IMP]
- heart development [IMP]
- homeostasis of number of cells [IMP]
- megakaryocyte development [IMP]
- megakaryocyte differentiation [IGI, IMP]
- mitral valve formation [IMP]
- negative regulation of fat cell differentiation [IMP]
- negative regulation of interleukin-4 biosynthetic process [ISO]
- negative regulation of mast cell differentiation [IDA]
- negative regulation of protein binding [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IBA, IDA, IMP, ISO, TAS]
- outflow tract morphogenesis [IMP]
- platelet formation [ISO]
- positive regulation of interferon-gamma biosynthetic process [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- primitive erythrocyte differentiation [IMP]
- regulation of chemokine production [IMP]
- regulation of definitive erythrocyte differentiation [ISO]
- transcription from RNA polymerase II promoter [IBA]
- transcriptional activation by promoter-enhancer looping [IDA]
- tricuspid valve formation [IMP]
- ventricular septum morphogenesis [IMP]
Gene Ontology Molecular Function- RNA polymerase II activating transcription factor binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IBA, ISO]
- RNA polymerase II transcription factor binding [ISO]
- protein binding [IPI]
- transcription corepressor activity [TAS]
- transcription factor binding [ISO]
- RNA polymerase II activating transcription factor binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IBA, ISO]
- RNA polymerase II transcription factor binding [ISO]
- protein binding [IPI]
- transcription corepressor activity [TAS]
- transcription factor binding [ISO]
Gene Ontology Cellular Component
CTBP1
Gene Ontology Biological Process
- Golgi organization [ISO]
- chromatin organization involved in regulation of transcription [ISO]
- negative regulation of histone H4 acetylation [ISO]
- negative regulation of histone acetylation [ISO]
- negative regulation of transcription from RNA polymerase II promoter [IMP, ISO]
- negative regulation of transcription, DNA-templated [IDA]
- positive regulation of histone deacetylation [ISO]
- regulation of cell cycle [ISO]
- transcription from RNA polymerase II promoter [ISO]
- white fat cell differentiation [IDA]
Gene Ontology Molecular Function- NAD binding [ISO]
- RNA polymerase II transcription corepressor activity [ISO]
- protein binding [IPI]
- protein domain specific binding [ISO]
- protein homodimerization activity [ISO]
- repressing transcription factor binding [ISO]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription factor binding [IPI, ISO]
- NAD binding [ISO]
- RNA polymerase II transcription corepressor activity [ISO]
- protein binding [IPI]
- protein domain specific binding [ISO]
- protein homodimerization activity [ISO]
- repressing transcription factor binding [ISO]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription factor binding [IPI, ISO]
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Translational isoforms of FOG1 regulate GATA1-interacting complexes.
Erythropoietic and megakaryocytic programs are directed by the transcription factor GATA1. Friend of GATA1 (FOG1), a protein interaction partner of GATA1, is critical for GATA1 function in multiple contexts. Previous work has shown that FOG1 recruits two multi-protein complexes, the nucleosome remodeling domain (NuRD) complex and a C-terminal binding protein (CTBP)-containing complex, into association with GATA1 to mediate activation and ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ZFPM1 CTBP1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low | - | BioGRID | - |
Curated By
- BioGRID