BAIT
BIN1
AMPH2, AMPHL, SH3P9
bridging integrator 1
GO Process (6)
GO Function (4)
GO Component (10)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RFX3
RP11-32F11.1
regulatory factor X, 3 (influences HLA class II expression)
GO Process (14)
GO Function (6)
GO Component (3)
Gene Ontology Biological Process
- cell maturation [ISS]
- cilium assembly [IBA, ISS]
- cilium-dependent cell motility [ISS]
- endocrine pancreas development [ISS]
- epithelial cilium movement involved in determination of left/right asymmetry [ISS]
- negative regulation of transcription, DNA-templated [IDA]
- positive regulation of transcription from RNA polymerase II promoter [ISS]
- positive regulation of transcription, DNA-templated [IDA]
- positive regulation of type B pancreatic cell development [ISS]
- regulation of insulin secretion [ISS]
- regulation of transcription from RNA polymerase II promoter [IBA]
- regulation of transcription, DNA-templated [ISS]
- transcription from RNA polymerase II promoter [TAS]
- type B pancreatic cell differentiation [IBA]
Gene Ontology Molecular Function- DNA binding [TAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IBA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [TAS]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [NAS]
- transcription regulatory region DNA binding [IDA]
- DNA binding [TAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IBA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [TAS]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [NAS]
- transcription regulatory region DNA binding [IDA]
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
An atlas of combinatorial transcriptional regulation in mouse and man.
Combinatorial interactions among transcription factors are critical to directing tissue-specific gene expression. To build a global atlas of these combinations, we have screened for physical interactions among the majority of human and mouse DNA-binding transcription factors (TFs). The complete networks contain 762 human and 877 mouse interactions. Analysis of the networks reveals that highly connected TFs are broadly expressed across ... [more]
Cell Mar. 05, 2010; 140(5);744-52 [Pubmed: 20211142]
Throughput
- High Throughput
Curated By
- BioGRID