BAIT
HOXB6
HOX2, HOX2B, HU-2, Hox-2.2
homeobox B6
GO Process (0)
GO Function (1)
GO Component (0)
Gene Ontology Molecular Function
Homo sapiens
PREY
TCF21
POD1, bHLHa23
transcription factor 21
GO Process (26)
GO Function (6)
GO Component (1)
Gene Ontology Biological Process
- Sertoli cell differentiation [ISS]
- branching involved in ureteric bud morphogenesis [ISS]
- branchiomeric skeletal muscle development [ISS]
- bronchiole development [ISS]
- diaphragm development [ISS]
- embryonic digestive tract morphogenesis [ISS]
- epithelial cell differentiation [ISS]
- gland development [ISS]
- glomerulus development [ISS]
- kidney development [ISS]
- lung alveolus development [ISS]
- lung morphogenesis [ISS]
- lung vasculature development [ISS]
- metanephric glomerular capillary formation [ISS]
- metanephric mesenchymal cell differentiation [ISS]
- morphogenesis of a branching structure [ISS]
- negative regulation of androgen receptor signaling pathway [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- palate development [ISS]
- positive regulation of transcription from RNA polymerase II promoter [ISS]
- reproductive structure development [ISS]
- respiratory system development [ISS]
- sex determination [ISS]
- spleen development [ISS]
- ureteric bud development [ISS]
- vasculature development [ISS]
Gene Ontology Molecular Function- E-box binding [ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISS]
- androgen receptor binding [ISS]
- bHLH transcription factor binding [IPI]
- protein dimerization activity [ISS]
- E-box binding [ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISS]
- androgen receptor binding [ISS]
- bHLH transcription factor binding [IPI]
- protein dimerization activity [ISS]
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
An atlas of combinatorial transcriptional regulation in mouse and man.
Combinatorial interactions among transcription factors are critical to directing tissue-specific gene expression. To build a global atlas of these combinations, we have screened for physical interactions among the majority of human and mouse DNA-binding transcription factors (TFs). The complete networks contain 762 human and 877 mouse interactions. Analysis of the networks reveals that highly connected TFs are broadly expressed across ... [more]
Cell Mar. 05, 2010; 140(5);744-52 [Pubmed: 20211142]
Throughput
- High Throughput
Curated By
- BioGRID