BAIT
TFAP2B
AP-2B, AP2-B, RP4-753D5.1
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
GO Process (35)
GO Function (16)
GO Component (1)
Gene Ontology Biological Process
- aorta morphogenesis [ISS]
- calcium ion homeostasis [ISS]
- cellular ammonia homeostasis [ISS]
- cellular creatinine homeostasis [ISS]
- cellular urea homeostasis [ISS]
- collecting duct development [ISS]
- distal tubule development [ISS]
- ductus arteriosus closure [ISS]
- fat cell differentiation [IEP]
- forelimb morphogenesis [ISS]
- glucose homeostasis [ISS]
- glucose metabolic process [IMP]
- hindlimb morphogenesis [ISS]
- kidney development [ISS]
- magnesium ion homeostasis [ISS]
- negative regulation of apoptotic process [IDA, ISS]
- negative regulation of cell proliferation [IDA]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- phosphate ion homeostasis [ISS]
- positive regulation of cell proliferation [IDA]
- positive regulation of neuron apoptotic process [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [IDA, IMP]
- positive regulation of urine volume [ISS]
- potassium ion homeostasis [ISS]
- regulation of BMP signaling pathway [ISS]
- regulation of cell differentiation [IDA]
- regulation of insulin secretion [IMP]
- regulation of transcription, DNA-templated [IDA]
- renal water homeostasis [ISS]
- retina layer formation [IEP]
- sodium ion homeostasis [ISS]
- sympathetic nervous system development [ISS]
Gene Ontology Molecular Function- DNA binding [TAS]
- RNA polymerase II core promoter sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity [ISS]
- RNA polymerase II transcription coactivator activity [ISS]
- RNA polymerase II transcription corepressor activity [ISS]
- cysteine-type endopeptidase inhibitor activity involved in apoptotic process [ISS]
- enhancer sequence-specific DNA binding [IDA]
- protein binding [IPI]
- protein dimerization activity [IDA]
- protein heterodimerization activity [IPI]
- protein homodimerization activity [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription coactivator activity [IDA]
- transcription corepressor activity [IDA]
- DNA binding [TAS]
- RNA polymerase II core promoter sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity [ISS]
- RNA polymerase II transcription coactivator activity [ISS]
- RNA polymerase II transcription corepressor activity [ISS]
- cysteine-type endopeptidase inhibitor activity involved in apoptotic process [ISS]
- enhancer sequence-specific DNA binding [IDA]
- protein binding [IPI]
- protein dimerization activity [IDA]
- protein heterodimerization activity [IPI]
- protein homodimerization activity [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription coactivator activity [IDA]
- transcription corepressor activity [IDA]
Homo sapiens
PREY
LZTR1
BTBD29, LZTR-1, SWNTS2
leucine-zipper-like transcription regulator 1
GO Process (2)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
An atlas of combinatorial transcriptional regulation in mouse and man.
Combinatorial interactions among transcription factors are critical to directing tissue-specific gene expression. To build a global atlas of these combinations, we have screened for physical interactions among the majority of human and mouse DNA-binding transcription factors (TFs). The complete networks contain 762 human and 877 mouse interactions. Analysis of the networks reveals that highly connected TFs are broadly expressed across ... [more]
Cell Mar. 05, 2010; 140(5);744-52 [Pubmed: 20211142]
Throughput
- High Throughput
Curated By
- BioGRID