BAIT
XBP1
TREB5, XBP-1, XBP2
X-box binding protein 1
GO Process (60)
GO Function (12)
GO Component (6)
Gene Ontology Biological Process
- activation of signaling protein activity involved in unfolded protein response [TAS]
- adipose tissue development [ISS]
- angiogenesis [ISS]
- cell growth [IDA]
- cellular protein metabolic process [TAS]
- cellular response to amino acid stimulus [ISS]
- cellular response to fluid shear stress [IDA]
- cellular response to fructose stimulus [ISS]
- cellular response to glucose starvation [ISS]
- cellular response to glucose stimulus [ISS]
- cellular response to insulin stimulus [ISS]
- cellular response to interleukin-4 [ISS]
- cellular response to laminar fluid shear stress [IDA]
- cellular response to lipopolysaccharide [IDA]
- cellular response to nutrient [ISS]
- cellular response to oxidative stress [IDA]
- cellular response to peptide hormone stimulus [ISS]
- cellular response to vascular endothelial growth factor stimulus [IDA]
- cellular triglyceride homeostasis [ISS]
- cholesterol homeostasis [ISS]
- endoplasmic reticulum unfolded protein response [ISS, TAS]
- endothelial cell proliferation [IDA]
- fatty acid homeostasis [ISS]
- immune response [TAS]
- liver development [ISS]
- negative regulation of apoptotic process [ISS]
- negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [IDA]
- negative regulation of endoplasmic reticulum unfolded protein response [IDA]
- negative regulation of myotube differentiation [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- neuron development [ISS]
- phosphatidylinositol 3-kinase signaling [IDA]
- positive regulation of B cell differentiation [IDA]
- positive regulation of MHC class II biosynthetic process [IMP]
- positive regulation of T cell differentiation [IDA]
- positive regulation of TOR signaling [IMP]
- positive regulation of autophagy [IDA]
- positive regulation of endoplasmic reticulum unfolded protein response [IMP]
- positive regulation of endothelial cell apoptotic process [IDA]
- positive regulation of fat cell differentiation [ISS]
- positive regulation of hepatocyte proliferation [ISS]
- positive regulation of histone methylation [IDA]
- positive regulation of immunoglobulin production [IDA]
- positive regulation of immunoglobulin secretion [ISS]
- positive regulation of interleukin-6 secretion [ISS]
- positive regulation of lactation [ISS]
- positive regulation of plasma cell differentiation [IDA]
- positive regulation of protein acetylation [IDA]
- positive regulation of protein phosphorylation [IDA]
- positive regulation of transcription factor import into nucleus [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP, ISS]
- positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [IDA, ISS]
- protein destabilization [IDA, IMP]
- regulation of protein stability [IDA]
- response to endoplasmic reticulum stress [IDA]
- response to insulin-like growth factor stimulus [ISS]
- sterol homeostasis [ISS]
- transcription from RNA polymerase II promoter [ISS]
- ubiquitin-dependent protein catabolic process [ISS]
- vascular endothelial growth factor receptor signaling pathway [IDA]
Gene Ontology Molecular Function- DNA binding [TAS]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- chromatin DNA binding [IDA]
- core promoter binding [ISS]
- enhancer sequence-specific DNA binding [IDA]
- protease binding [IPI]
- protein binding [IPI]
- protein heterodimerization activity [IDA]
- protein kinase binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription regulatory region DNA binding [IDA]
- ubiquitin protein ligase binding [IPI]
- DNA binding [TAS]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- chromatin DNA binding [IDA]
- core promoter binding [ISS]
- enhancer sequence-specific DNA binding [IDA]
- protease binding [IPI]
- protein binding [IPI]
- protein heterodimerization activity [IDA]
- protein kinase binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription regulatory region DNA binding [IDA]
- ubiquitin protein ligase binding [IPI]
Gene Ontology Cellular Component
Homo sapiens
PREY
FUBP3
FBP3, RP11-57C19.3
far upstream element (FUSE) binding protein 3
GO Process (4)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
An atlas of combinatorial transcriptional regulation in mouse and man.
Combinatorial interactions among transcription factors are critical to directing tissue-specific gene expression. To build a global atlas of these combinations, we have screened for physical interactions among the majority of human and mouse DNA-binding transcription factors (TFs). The complete networks contain 762 human and 877 mouse interactions. Analysis of the networks reveals that highly connected TFs are broadly expressed across ... [more]
Cell Mar. 05, 2010; 140(5);744-52 [Pubmed: 20211142]
Throughput
- High Throughput
Curated By
- BioGRID