BAIT
NCOA3
2010305B15Rik, AW321064, Actr, Aib1, KAT13B, Rac3, Src3, Tram-1, Tram1, bHLHe42, p/Cip, pCip, RP23-120P1.1
nuclear receptor coactivator 3
GO Process (17)
GO Function (12)
GO Component (6)
Gene Ontology Biological Process
- cellular response to hormone stimulus [IBA]
- developmental growth [IMP]
- histone acetylation [ISO]
- intracellular receptor signaling pathway [IBA]
- labyrinthine layer morphogenesis [IGI]
- mammary gland branching involved in thelarche [IMP]
- multicellular organism growth [IMP]
- negative regulation of apoptotic process [ISO]
- positive regulation of cell growth [ISO]
- positive regulation of gene expression [ISO]
- positive regulation of intracellular estrogen receptor signaling pathway [ISO]
- positive regulation of intracellular steroid hormone receptor signaling pathway [ISO]
- positive regulation of keratinocyte differentiation [ISO]
- positive regulation of sequence-specific DNA binding transcription factor activity [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IBA, ISO]
- regulation of RNA biosynthetic process [ISO]
- vagina development [IMP]
Gene Ontology Molecular Function- RNA polymerase II regulatory region DNA binding [ISO]
- androgen receptor binding [ISO]
- chromatin binding [IDA]
- estrogen receptor binding [ISO]
- histone acetyltransferase activity [ISO]
- ligand-dependent nuclear receptor binding [IBA, ISO]
- ligand-dependent nuclear receptor transcription coactivator activity [IBA, ISO]
- nuclear hormone receptor binding [IBA, ISO]
- peroxisome proliferator activated receptor binding [ISO]
- protein N-terminus binding [ISO]
- protein complex binding [ISO]
- transcription coactivator activity [ISO]
- RNA polymerase II regulatory region DNA binding [ISO]
- androgen receptor binding [ISO]
- chromatin binding [IDA]
- estrogen receptor binding [ISO]
- histone acetyltransferase activity [ISO]
- ligand-dependent nuclear receptor binding [IBA, ISO]
- ligand-dependent nuclear receptor transcription coactivator activity [IBA, ISO]
- nuclear hormone receptor binding [IBA, ISO]
- peroxisome proliferator activated receptor binding [ISO]
- protein N-terminus binding [ISO]
- protein complex binding [ISO]
- transcription coactivator activity [ISO]
Gene Ontology Cellular Component
Mus musculus
PREY
TRPS1
AI115454, AI447310, D15Ertd586e
trichorhinophalangeal syndrome I (human)
GO Process (6)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- chondrocyte differentiation [IGI]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription, DNA-templated [IPI]
- positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [IGI]
- regulation of chondrocyte differentiation [IMP]
- transmembrane receptor protein serine/threonine kinase signaling pathway [IGI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- nucleoplasm [ISO]
- nucleus [IDA, ISO]
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
An atlas of combinatorial transcriptional regulation in mouse and man.
Combinatorial interactions among transcription factors are critical to directing tissue-specific gene expression. To build a global atlas of these combinations, we have screened for physical interactions among the majority of human and mouse DNA-binding transcription factors (TFs). The complete networks contain 762 human and 877 mouse interactions. Analysis of the networks reveals that highly connected TFs are broadly expressed across ... [more]
Cell Mar. 05, 2010; 140(5);744-52 [Pubmed: 20211142]
Throughput
- High Throughput
Curated By
- BioGRID