BAIT
NFATC3
C80703, D8Ertd281e, NFAT4, NFATx
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3
GO Process (21)
GO Function (10)
GO Component (5)
Gene Ontology Biological Process
- T cell differentiation [IMP]
- blood vessel remodeling [IMP]
- calcineurin-NFAT signaling cascade [IGI]
- cardiac muscle hypertrophy in response to stress [IGI]
- cellular respiration [IMP]
- cellular response to calcium ion [IDA]
- cellular response to lithium ion [IDA]
- heart development [IGI]
- muscle cell development [IGI]
- myotube cell development [IMP]
- myotube differentiation [IMP]
- patterning of blood vessels [IGI]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, ISO]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of store-operated calcium entry [IMP]
- regulation of transcription, DNA-templated [IDA]
- response to hypoxia [IDA]
- skeletal muscle fiber development [IMP]
- smooth muscle cell differentiation [IGI]
- thymus development [IMP]
- transcription from RNA polymerase II promoter [ISO]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- chromatin binding [IDA]
- core promoter proximal region sequence-specific DNA binding [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription factor binding [IDA]
- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- chromatin binding [IDA]
- core promoter proximal region sequence-specific DNA binding [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription factor binding [IDA]
Mus musculus
PREY
NFATC4
3110041H08Rik, AW107667, AW546455, Nfat3
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4
GO Process (20)
GO Function (8)
GO Component (6)
Gene Ontology Biological Process
- calcineurin-NFAT signaling cascade [IGI]
- cellular respiration [IDA]
- cellular response to UV [IGI]
- cellular response to lithium ion [IDA]
- heart development [IGI]
- intrinsic apoptotic signaling pathway in response to DNA damage [IGI, IMP]
- muscle cell development [IGI]
- negative regulation of chromatin binding [IDA]
- negative regulation of dendrite morphogenesis [IMP]
- negative regulation of synapse maturation [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- patterning of blood vessels [IGI]
- positive regulation of apoptotic process [IMP]
- positive regulation of apoptotic signaling pathway [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP]
- positive regulation of tumor necrosis factor production [IMP]
- regulation of synaptic plasticity [ISO]
- regulation of transcription, DNA-templated [IDA, ISO]
- smooth muscle cell differentiation [IGI]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- peroxisome proliferator activated receptor binding [ISO]
- protein binding [IPI]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- transcription factor binding [IDA, ISO]
- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- peroxisome proliferator activated receptor binding [ISO]
- protein binding [IPI]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- transcription factor binding [IDA, ISO]
Gene Ontology Cellular Component
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
An atlas of combinatorial transcriptional regulation in mouse and man.
Combinatorial interactions among transcription factors are critical to directing tissue-specific gene expression. To build a global atlas of these combinations, we have screened for physical interactions among the majority of human and mouse DNA-binding transcription factors (TFs). The complete networks contain 762 human and 877 mouse interactions. Analysis of the networks reveals that highly connected TFs are broadly expressed across ... [more]
Cell Mar. 05, 2010; 140(5);744-52 [Pubmed: 20211142]
Throughput
- High Throughput
Curated By
- BioGRID