BAIT
PAX8
Pax-8, RP23-218B17.4
paired box 8
GO Process (27)
GO Function (8)
GO Component (3)
Gene Ontology Biological Process
- cell differentiation [IMP]
- cellular response to gonadotropin stimulus [ISO]
- inner ear morphogenesis [IGI]
- mesonephros development [IMP]
- metanephric distal convoluted tubule development [IMP]
- metanephric nephron tubule formation [IMP]
- metanephros development [IGI]
- negative regulation of apoptotic process involved in metanephric collecting duct development [IMP]
- negative regulation of apoptotic process involved in metanephric nephron tubule development [IMP]
- negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis [IMP]
- negative regulation of mesenchymal cell apoptotic process involved in metanephros development [IMP]
- organ morphogenesis [TAS]
- positive regulation of branching involved in ureteric bud morphogenesis [IMP]
- positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [IMP]
- positive regulation of metanephric DCT cell differentiation [IMP]
- positive regulation of thyroid hormone generation [IMP, ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of transcription, DNA-templated [IDA, IGI, IMP, ISO]
- pronephros development [IMP]
- regulation of apoptotic process [IMP]
- regulation of metanephric nephron tubule epithelial cell differentiation [IMP]
- regulation of thyroid-stimulating hormone secretion [ISO]
- regulation of transcription, DNA-templated [ISO, TAS]
- thyroid gland development [IGI, IMP, ISO]
- transcription from RNA polymerase II promoter [ISO]
- transcription, DNA-templated [IDA, ISO]
- urogenital system development [IGI]
Gene Ontology Molecular Function- DNA binding [ISO, ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- RNA polymerase II core promoter sequence-specific DNA binding [ISO]
- protein binding [IPI]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [ISO, TAS]
- transcription regulatory region DNA binding [IDA, ISO]
- DNA binding [ISO, ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- RNA polymerase II core promoter sequence-specific DNA binding [ISO]
- protein binding [IPI]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [ISO, TAS]
- transcription regulatory region DNA binding [IDA, ISO]
Gene Ontology Cellular Component
Mus musculus
PREY
JADE1
AU041499, D530048A03Rik, Phf17, mKIAA1807
jade family PHD finger 1
GO Process (7)
GO Function (1)
GO Component (6)
Gene Ontology Biological Process
- histone H3 acetylation [ISO]
- histone H4-K12 acetylation [ISO]
- histone H4-K5 acetylation [ISO]
- histone H4-K8 acetylation [ISO]
- negative regulation of G1/S transition of mitotic cell cycle [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- transcription from RNA polymerase II promoter [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
An atlas of combinatorial transcriptional regulation in mouse and man.
Combinatorial interactions among transcription factors are critical to directing tissue-specific gene expression. To build a global atlas of these combinations, we have screened for physical interactions among the majority of human and mouse DNA-binding transcription factors (TFs). The complete networks contain 762 human and 877 mouse interactions. Analysis of the networks reveals that highly connected TFs are broadly expressed across ... [more]
Cell Mar. 05, 2010; 140(5);744-52 [Pubmed: 20211142]
Throughput
- High Throughput
Curated By
- BioGRID