BAIT
RELA
p65
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
GO Process (41)
GO Function (25)
GO Component (8)
Gene Ontology Biological Process
- NIK/NF-kappaB signaling [IBA]
- cellular response to hydrogen peroxide [ISO]
- cellular response to interleukin-1 [ISO]
- cellular response to interleukin-6 [ISO]
- cellular response to nicotine [ISO]
- cellular response to peptide hormone stimulus [ISO]
- cellular response to stress [IBA]
- cellular response to tumor necrosis factor [ISO]
- cytokine-mediated signaling pathway [ISO]
- defense response [IMP]
- hair follicle development [IMP]
- inflammatory response [ISO]
- innate immune response [IBA]
- liver development [IMP]
- negative regulation of apoptotic process [IDA, ISO]
- negative regulation of extrinsic apoptotic signaling pathway [IDA, ISO]
- negative regulation of insulin receptor signaling pathway [ISO]
- negative regulation of protein catabolic process [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IBA, ISO]
- negative regulation of transcription, DNA-templated [ISO]
- nucleotide-binding oligomerization domain containing 2 signaling pathway [ISO]
- organ morphogenesis [IMP]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IDA]
- positive regulation of NF-kappaB transcription factor activity [IDA, ISO]
- positive regulation of Schwann cell differentiation [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of chondrocyte differentiation [ISO]
- positive regulation of interleukin-12 biosynthetic process [IDA]
- positive regulation of miRNA metabolic process [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IBA, ISO]
- positive regulation of transcription, DNA-templated [IDA, IMP, ISO, TAS]
- regulation of inflammatory response [IDA]
- regulation of transcription from RNA polymerase II promoter [IDA]
- response to UV-B [ISO]
- response to bacterium [IDA]
- response to cytokine [IBA]
- response to interleukin-1 [ISO]
- response to muramyl dipeptide [IDA]
- response to muscle stretch [IDA]
- response to organic substance [ISO]
- transcription from RNA polymerase II promoter [ISO]
Gene Ontology Molecular Function- DNA binding [IDA, ISO]
- NF-kappaB binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding [ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA, ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- activating transcription factor binding [ISO]
- ankyrin repeat binding [IPI]
- chromatin binding [IDA, ISO]
- enzyme binding [IPI]
- identical protein binding [ISO]
- phosphate ion binding [ISO]
- protein N-terminus binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein kinase binding [IPI, ISO]
- repressing transcription factor binding [ISO]
- sequence-specific DNA binding [IDA, ISO]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- transcription factor binding [ISO]
- transcription regulatory region DNA binding [ISO]
- ubiquitin protein ligase binding [ISO]
- DNA binding [IDA, ISO]
- NF-kappaB binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding [ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA, ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- activating transcription factor binding [ISO]
- ankyrin repeat binding [IPI]
- chromatin binding [IDA, ISO]
- enzyme binding [IPI]
- identical protein binding [ISO]
- phosphate ion binding [ISO]
- protein N-terminus binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein kinase binding [IPI, ISO]
- repressing transcription factor binding [ISO]
- sequence-specific DNA binding [IDA, ISO]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- transcription factor binding [ISO]
- transcription regulatory region DNA binding [ISO]
- ubiquitin protein ligase binding [ISO]
Gene Ontology Cellular Component
Mus musculus
PREY
PIAS3
Pias3l
protein inhibitor of activated STAT 3
GO Process (4)
GO Function (6)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
An atlas of combinatorial transcriptional regulation in mouse and man.
Combinatorial interactions among transcription factors are critical to directing tissue-specific gene expression. To build a global atlas of these combinations, we have screened for physical interactions among the majority of human and mouse DNA-binding transcription factors (TFs). The complete networks contain 762 human and 877 mouse interactions. Analysis of the networks reveals that highly connected TFs are broadly expressed across ... [more]
Cell Mar. 05, 2010; 140(5);744-52 [Pubmed: 20211142]
Throughput
- High Throughput
Curated By
- BioGRID