BAIT
TCF3
A1, AA408400, ALF2, AW209082, E12, E12/E47, E2A, E47, ME2, Pan1, Pan2, TCF-3, Tcfe2a, VDIR, bHLHb21
transcription factor 3
GO Process (26)
GO Function (21)
GO Component (8)
Gene Ontology Biological Process
- B cell lineage commitment [ISO]
- Peyer's patch development [IGI]
- T cell differentiation in thymus [IMP]
- cell development [IGI]
- gastrulation [IGI]
- histone H3 acetylation [IMP]
- histone H4 acetylation [IMP]
- immunoglobulin V(D)J recombination [IMP, ISO]
- lymphocyte differentiation [IMP]
- natural killer cell differentiation [IGI]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of B cell proliferation [ISO]
- positive regulation of cell cycle [ISO]
- positive regulation of gene expression [IMP, ISO]
- positive regulation of neuron differentiation [IDA]
- positive regulation of sequence-specific DNA binding transcription factor activity [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP, ISO]
- positive regulation of transcription, DNA-templated [IDA, IGI, ISO]
- protein stabilization [IDA]
- regulation of G1/S transition of mitotic cell cycle [ISO]
- regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of transcription, DNA-templated [IDA, IGI, TAS]
- response to drug [IMP]
- response to lipopolysaccharide [IMP]
- transcription from RNA polymerase II promoter [IMP]
- transcription, DNA-templated [ISO]
Gene Ontology Molecular Function- DNA binding [IDA, ISO]
- E-box binding [IDA, ISO]
- PDZ domain binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA, IMP, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, IMP]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IMP]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IMP]
- bHLH transcription factor binding [ISO]
- chromatin binding [IDA]
- mitogen-activated protein kinase kinase kinase binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [IDA, IPI, ISO]
- protein homodimerization activity [IDA, ISO]
- repressing transcription factor binding [ISO]
- sequence-specific DNA binding [IDA, IGI, ISO]
- sequence-specific DNA binding transcription factor activity [ISO, TAS]
- transcription coactivator activity [ISO]
- transcription factor binding [IPI, ISO]
- transcription regulatory region DNA binding [ISO]
- vitamin D response element binding [ISO]
- DNA binding [IDA, ISO]
- E-box binding [IDA, ISO]
- PDZ domain binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA, IMP, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, IMP]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IMP]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IMP]
- bHLH transcription factor binding [ISO]
- chromatin binding [IDA]
- mitogen-activated protein kinase kinase kinase binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [IDA, IPI, ISO]
- protein homodimerization activity [IDA, ISO]
- repressing transcription factor binding [ISO]
- sequence-specific DNA binding [IDA, IGI, ISO]
- sequence-specific DNA binding transcription factor activity [ISO, TAS]
- transcription coactivator activity [ISO]
- transcription factor binding [IPI, ISO]
- transcription regulatory region DNA binding [ISO]
- vitamin D response element binding [ISO]
Gene Ontology Cellular Component
Mus musculus
PREY
PDLIM4
Ril, RP23-354D12.3
PDZ and LIM domain 4
GO Process (1)
GO Function (2)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
An atlas of combinatorial transcriptional regulation in mouse and man.
Combinatorial interactions among transcription factors are critical to directing tissue-specific gene expression. To build a global atlas of these combinations, we have screened for physical interactions among the majority of human and mouse DNA-binding transcription factors (TFs). The complete networks contain 762 human and 877 mouse interactions. Analysis of the networks reveals that highly connected TFs are broadly expressed across ... [more]
Cell Mar. 05, 2010; 140(5);744-52 [Pubmed: 20211142]
Throughput
- High Throughput
Curated By
- BioGRID