BAIT
SALL4
5730441M18Rik, AA407717, AL022809, AW536104, C330011P20Rik, C78083, C78563, Tex20, RP23-354I18.1
sal-like 4 (Drosophila)
GO Process (11)
GO Function (1)
GO Component (6)
Gene Ontology Biological Process
- embryonic limb morphogenesis [IGI, IMP]
- heart development [IMP]
- in utero embryonic development [IMP]
- inner cell mass cell proliferation [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IGI]
- neural tube closure [IGI, IMP]
- neural tube development [IGI]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI]
- stem cell maintenance [IMP]
- tissue development [IMP]
- ventricular septum development [IGI, IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
USP9X
5730589N07Rik, AA407302, AA407699, AL022658, AL022749, Dffrx, FAF-X, Fafl, RP23-216M21.1
ubiquitin specific peptidase 9, X chromosome
GO Process (13)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
- BMP signaling pathway [ISO]
- axon extension [IMP, ISO]
- cellular response to transforming growth factor beta stimulus [IMP]
- cerebellar cortex structural organization [IMP]
- hippocampus development [IMP]
- in utero embryonic development [IGI]
- neuron migration [IMP, ISO]
- neuron projection extension [IGI]
- post-embryonic development [IMP]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IBA]
- protein deubiquitination [IBA, ISO]
- regulation of proteasomal protein catabolic process [IBA]
- transforming growth factor beta receptor signaling pathway [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
An Oct4-centered protein interaction network in embryonic stem cells.
Transcription factors, such as Oct4, are critical for establishing and maintaining pluripotent cell identity. Whereas the genomic locations of several pluripotency transcription factors have been reported, the spectrum of their interaction partners is underexplored. Here, we use an improved affinity protocol to purify Oct4-interacting proteins from mouse embryonic stem cells (ESCs). Subsequent purification of Oct4 partners Sall4, Tcfcp2l1, Dax1, and ... [more]
Cell Stem Cell Apr. 02, 2010; 6(4);369-81 [Pubmed: 20362541]
Throughput
- High Throughput
Curated By
- BioGRID