BAIT
TFCP2L1
1810030F05Rik, 4932442M07Rik, AA575098, Cp2l1, Crtr-1, D930018N21Rik, LBP-9, Tcfcp2l1
transcription factor CP2-like 1
GO Process (8)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- cell morphogenesis [IMP]
- cytoplasm organization [IMP]
- determination of adult lifespan [IMP]
- epithelial cell maturation [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of growth [IMP]
- regulation of transcription, DNA-templated [IBA]
- salivary gland development [IMP]
Gene Ontology Molecular Function
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
An Oct4-centered protein interaction network in embryonic stem cells.
Transcription factors, such as Oct4, are critical for establishing and maintaining pluripotent cell identity. Whereas the genomic locations of several pluripotency transcription factors have been reported, the spectrum of their interaction partners is underexplored. Here, we use an improved affinity protocol to purify Oct4-interacting proteins from mouse embryonic stem cells (ESCs). Subsequent purification of Oct4 partners Sall4, Tcfcp2l1, Dax1, and ... [more]
Cell Stem Cell Apr. 02, 2010; 6(4);369-81 [Pubmed: 20362541]
Throughput
- High Throughput
Curated By
- BioGRID