BAIT
NR0B1
AHX, Ahc, Ahch, DAX-1, Dax1, RP23-346H6.1
nuclear receptor subfamily 0, group B, member 1
GO Process (19)
GO Function (13)
GO Component (4)
Gene Ontology Biological Process
- Leydig cell differentiation [IMP]
- Sertoli cell differentiation [IMP]
- adrenal gland development [IGI, ISO]
- cell differentiation [IGI]
- gonad development [ISO]
- intracellular receptor signaling pathway [ISO]
- male gonad development [IMP, ISO]
- male sex determination [IGI, IMP]
- negative regulation of cell differentiation [IMP]
- negative regulation of intracellular steroid hormone receptor signaling pathway [ISO]
- negative regulation of sequence-specific DNA binding transcription factor activity [ISO]
- negative regulation of transcription from RNA polymerase II promoter [IGI, IMP, ISO]
- negative regulation of transcription, DNA-templated [IDA, ISO]
- protein localization [ISO]
- response to immobilization stress [IMP]
- sex determination [IGI]
- spermatogenesis [IMP]
- steroid biosynthetic process [ISO]
- transcription from RNA polymerase II promoter [ISO]
Gene Ontology Molecular Function- AF-2 domain binding [ISO]
- DNA binding [ISO]
- DNA hairpin binding [ISO]
- RNA binding [IDA, ISO]
- double-stranded DNA binding [ISO]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [ISO]
- protein binding [IPI]
- protein domain specific binding [ISO]
- protein homodimerization activity [ISO]
- sequence-specific DNA binding [ISO]
- steroid hormone receptor binding [ISO]
- transcription corepressor activity [IGI, ISO]
- transcription factor binding [ISO]
- AF-2 domain binding [ISO]
- DNA binding [ISO]
- DNA hairpin binding [ISO]
- RNA binding [IDA, ISO]
- double-stranded DNA binding [ISO]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [ISO]
- protein binding [IPI]
- protein domain specific binding [ISO]
- protein homodimerization activity [ISO]
- sequence-specific DNA binding [ISO]
- steroid hormone receptor binding [ISO]
- transcription corepressor activity [IGI, ISO]
- transcription factor binding [ISO]
Mus musculus
PREY
SP1
1110003E12Rik, AA450830, AI845540, Sp1-1
trans-acting transcription factor 1
GO Process (18)
GO Function (20)
GO Component (4)
Gene Ontology Biological Process
- definitive hemopoiesis [IGI]
- embryonic camera-type eye morphogenesis [IGI]
- embryonic placenta development [IGI]
- embryonic process involved in female pregnancy [IGI]
- embryonic skeletal system development [IGI]
- enucleate erythrocyte differentiation [IGI]
- in utero embryonic development [IGI]
- liver development [IGI]
- lung development [IGI]
- megakaryocyte differentiation [IGI]
- ossification [IGI]
- positive regulation by host of viral transcription [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP, ISO]
- positive regulation of transcription, DNA-templated [IDA, ISO]
- regulation of transcription from RNA polymerase II promoter [ISO]
- regulation of transcription, DNA-templated [IMP, ISO]
- transcription from RNA polymerase II promoter [IDA]
- trophectodermal cell differentiation [IGI]
Gene Ontology Molecular Function- DNA binding [IDA, ISO, ISS]
- HMG box domain binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- RNA polymerase II core promoter sequence-specific DNA binding [IDA]
- RNA polymerase II repressing transcription factor binding [IPI]
- bHLH transcription factor binding [IPI]
- core promoter proximal region sequence-specific DNA binding [IDA]
- core promoter sequence-specific DNA binding [IDA]
- double-stranded DNA binding [IDA, ISO]
- enhancer binding [IDA]
- histone acetyltransferase binding [ISO]
- histone deacetylase binding [ISO]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- sequence-specific DNA binding [IDA, ISO]
- sequence-specific DNA binding transcription factor activity [IDA, IMP, ISO]
- transcription factor binding [ISO]
- transcription regulatory region DNA binding [ISO]
- DNA binding [IDA, ISO, ISS]
- HMG box domain binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- RNA polymerase II core promoter sequence-specific DNA binding [IDA]
- RNA polymerase II repressing transcription factor binding [IPI]
- bHLH transcription factor binding [IPI]
- core promoter proximal region sequence-specific DNA binding [IDA]
- core promoter sequence-specific DNA binding [IDA]
- double-stranded DNA binding [IDA, ISO]
- enhancer binding [IDA]
- histone acetyltransferase binding [ISO]
- histone deacetylase binding [ISO]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- sequence-specific DNA binding [IDA, ISO]
- sequence-specific DNA binding transcription factor activity [IDA, IMP, ISO]
- transcription factor binding [ISO]
- transcription regulatory region DNA binding [ISO]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A protein interaction network for pluripotency of embryonic stem cells.
Embryonic stem (ES) cells are pluripotent and of therapeutic potential in regenerative medicine. Understanding pluripotency at the molecular level should illuminate fundamental properties of stem cells and the process of cellular reprogramming. Through cell fusion the embryonic cell phenotype can be imposed on somatic cells, a process promoted by the homeodomain protein Nanog, which is central to the maintenance of ... [more]
Nature Nov. 16, 2006; 444(7117);364-8 [Pubmed: 17093407]
Throughput
- High Throughput
Curated By
- BioGRID