BAIT
ZFP281
Znf281
zinc finger protein 281
GO Process (9)
GO Function (8)
GO Component (2)
Gene Ontology Biological Process
- embryonic body morphogenesis [IMP]
- negative regulation of gene expression [ISO]
- negative regulation of nucleic acid-templated transcription [IMP]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of transcription, DNA-templated [IMP]
- stem cell differentiation [IMP]
- transcription from RNA polymerase II promoter [ISO]
Gene Ontology Molecular Function- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [ISO]
- core promoter binding [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [IMP, ISO]
- transcription corepressor activity [IMP]
- transcription regulatory region DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [ISO]
- core promoter binding [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [IMP, ISO]
- transcription corepressor activity [IMP]
- transcription regulatory region DNA binding [ISO]
Gene Ontology Cellular Component
- nucleoplasm [ISO]
- nucleus [ISO]
Mus musculus
PREY
EWSR1
Ews, Ewsh, RP23-338J18.1
Ewing sarcoma breakpoint region 1
GO Process (0)
GO Function (1)
GO Component (1)
Gene Ontology Molecular Function
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A protein interaction network for pluripotency of embryonic stem cells.
Embryonic stem (ES) cells are pluripotent and of therapeutic potential in regenerative medicine. Understanding pluripotency at the molecular level should illuminate fundamental properties of stem cells and the process of cellular reprogramming. Through cell fusion the embryonic cell phenotype can be imposed on somatic cells, a process promoted by the homeodomain protein Nanog, which is central to the maintenance of ... [more]
Nature Nov. 16, 2006; 444(7117);364-8 [Pubmed: 17093407]
Throughput
- High Throughput
Curated By
- BioGRID