BAIT
MTF2
9230112N11Rik, AA537621, C76717, M96, Pcl2
metal response element binding transcription factor 2
GO Process (7)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- negative regulation of histone H3-K27 methylation [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of histone H3-K27 methylation [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- segment specification [IMP]
- stem cell differentiation [IMP]
- stem cell maintenance [IMP]
Gene Ontology Molecular Function
Mus musculus
PREY
STK38
5830476G13Rik, 9530097A09Rik, AA617404, Ndr1
serine/threonine kinase 38
GO Process (4)
GO Function (5)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells.
Trimethylation on histone H3 lysine 27 (H3K27me3) by Polycomb repressive complex 2 (PRC2) regulates the balance between self-renewal and differentiation of embryonic stem cells (ESCs). The mechanisms controlling the activity and recruitment of PRC2 are largely unknown. Here we demonstrate that the founding member of the Jumonji family, JMJ (JUMONJI or JARID2), is associated with PRC2, colocalizes with PRC2 and ... [more]
Cell Dec. 24, 2009; 139(7);1303-14 [Pubmed: 20064376]
Throughput
- High Throughput
Curated By
- BioGRID