BAIT
MTF2
9230112N11Rik, AA537621, C76717, M96, Pcl2
metal response element binding transcription factor 2
GO Process (7)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- negative regulation of histone H3-K27 methylation [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of histone H3-K27 methylation [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- segment specification [IMP]
- stem cell differentiation [IMP]
- stem cell maintenance [IMP]
Gene Ontology Molecular Function
Mus musculus
PREY
ICE1
C77245, mKIAA0947
interactor of little elongation complex ELL subunit 1
GO Process (5)
GO Function (0)
GO Component (4)
Gene Ontology Biological Process
- positive regulation of intracellular protein transport [ISO]
- positive regulation of protein complex assembly [ISO]
- positive regulation of transcription from RNA polymerase III promoter [ISO]
- snRNA transcription from RNA polymerase II promoter [ISO]
- snRNA transcription from RNA polymerase III promoter [ISO]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells.
Trimethylation on histone H3 lysine 27 (H3K27me3) by Polycomb repressive complex 2 (PRC2) regulates the balance between self-renewal and differentiation of embryonic stem cells (ESCs). The mechanisms controlling the activity and recruitment of PRC2 are largely unknown. Here we demonstrate that the founding member of the Jumonji family, JMJ (JUMONJI or JARID2), is associated with PRC2, colocalizes with PRC2 and ... [more]
Cell Dec. 24, 2009; 139(7);1303-14 [Pubmed: 20064376]
Throughput
- High Throughput
Curated By
- BioGRID