BAIT
SMARCA2
2610209L14Rik, SNF2alpha, Snf2l2, brahma, brm
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
GO Process (9)
GO Function (4)
GO Component (9)
Gene Ontology Biological Process
- aortic smooth muscle cell differentiation [IMP]
- chromatin organization [TAS]
- negative regulation of cell growth [ISO]
- negative regulation of cell proliferation [IMP]
- negative regulation of transcription, DNA-templated [ISO]
- nucleosome assembly [TAS]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- transcription from RNA polymerase II promoter [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
SFPQ
1110004P21Rik, 2810416M14Rik, 5730453G22Rik, 9030402K04Rik, AU021830, D4Ertd314e, Gm12940, OTTMUSG00000009329, PSF, REP1, RP23-153M14.2
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
GO Process (7)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- alternative mRNA splicing, via spliceosome [ISO]
- histone H3 deacetylation [IMP]
- negative regulation of circadian rhythm [IMP]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [ISO]
- regulation of circadian rhythm [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency.
Mammalian SWI/SNF [also called BAF (Brg/Brahma-associated factors)] ATP-dependent chromatin remodeling complexes are essential for formation of the totipotent and pluripotent cells of the early embryo. In addition, subunits of this complex have been recovered in screens for genes required for nuclear reprogramming in Xenopus and mouse embryonic stem cell (ES) morphology. However, the mechanism underlying the roles of these complexes ... [more]
Proc. Natl. Acad. Sci. U.S.A. Mar. 31, 2009; 106(13);5181-6 [Pubmed: 19279220]
Throughput
- Low Throughput
Curated By
- BioGRID