OGT
Gene Ontology Biological Process
- apoptotic process [ISO, ISS]
- cellular response to glucose stimulus [IMP]
- cellular response to insulin stimulus [IEP]
- cellular response to lipopolysaccharide [IMP]
- cellular response to retinoic acid [ISO]
- cellular response to toxic substance [IEP]
- circadian regulation of gene expression [ISO, ISS]
- forebrain development [IEP]
- glucosamine metabolic process [IDA, IMP]
- histone H3-K4 trimethylation [ISO, ISS]
- histone H4-K16 acetylation [ISO, ISS]
- histone H4-K5 acetylation [ISO, ISS]
- histone H4-K8 acetylation [ISO, ISS]
- intracellular distribution of mitochondria [IMP]
- negative regulation of cell death [IMP]
- negative regulation of cellular response to hypoxia [IMP]
- negative regulation of peptidyl-serine phosphorylation [IMP]
- negative regulation of peptidyl-threonine phosphorylation [IMP]
- negative regulation of protein phosphorylation [IMP]
- negative regulation of protein targeting to membrane [IMP]
- negative regulation of protein ubiquitination [ISO, ISS]
- phosphatidylinositol-mediated signaling [ISO, ISS]
- positive regulation of catalytic activity [ISO]
- positive regulation of cell size [IMP]
- positive regulation of gene expression [IMP]
- positive regulation of granulocyte differentiation [ISO]
- positive regulation of histone H3-K27 methylation [ISO, ISS]
- positive regulation of histone H3-K4 methylation [ISO]
- positive regulation of protein localization to nucleus [IMP]
- positive regulation of protein phosphorylation [IMP]
- positive regulation of proteolysis [ISO, ISS]
- positive regulation of reactive oxygen species biosynthetic process [IMP]
- positive regulation of transcription from RNA polymerase II promoter [ISO, ISS]
- protein O-linked glycosylation [IDA, IMP, ISO]
- protein heterotrimerization [IDA]
- protein homotrimerization [IDA]
- regulation of Rac protein signal transduction [ISO]
- regulation of gluconeogenesis involved in cellular glucose homeostasis [ISO, ISS]
- regulation of glycolytic process [ISO, ISS]
- regulation of insulin receptor signaling pathway [ISO]
- response to insulin [ISO]
Gene Ontology Molecular Function- enzyme activator activity [ISO]
- histone acetyltransferase activity (H4-K16 specific) [ISO, ISS]
- histone acetyltransferase activity (H4-K5 specific) [ISO, ISS]
- histone acetyltransferase activity (H4-K8 specific) [ISO, ISS]
- monosaccharide binding [IDA]
- peptide binding [IDA]
- phosphatidylinositol-3,4,5-trisphosphate binding [ISO, ISS]
- protein N-acetylglucosaminyltransferase activity [IDA, ISO]
- protein O-GlcNAc transferase activity [ISO, ISS]
- protein binding [IPI]
- protein domain specific binding [IPI]
- transcription factor binding [IPI]
- enzyme activator activity [ISO]
- histone acetyltransferase activity (H4-K16 specific) [ISO, ISS]
- histone acetyltransferase activity (H4-K5 specific) [ISO, ISS]
- histone acetyltransferase activity (H4-K8 specific) [ISO, ISS]
- monosaccharide binding [IDA]
- peptide binding [IDA]
- phosphatidylinositol-3,4,5-trisphosphate binding [ISO, ISS]
- protein N-acetylglucosaminyltransferase activity [IDA, ISO]
- protein O-GlcNAc transferase activity [ISO, ISS]
- protein binding [IPI]
- protein domain specific binding [IPI]
- transcription factor binding [IPI]
Gene Ontology Cellular Component
- MLL5-L complex [ISO]
- cytoplasm [IDA, ISO]
- cytosol [IDA, ISO]
- euchromatin [IDA]
- histone acetyltransferase complex [ISO, ISS]
- microtubule organizing center [ISO]
- mitochondrion [IDA]
- neuron projection [IDA]
- neuronal cell body [IDA]
- nucleoplasm [ISO]
- nucleus [IDA, ISO]
- plasma membrane [ISO, ISS]
- zymogen granule [IDA]
ATXN10
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Ataxin-10 interacts with O-linked beta-N-acetylglucosamine transferase in the brain.
Modification by O-GlcNAc involves a growing number of eucaryotic nuclear and cytosolic proteins. Glycosylation of intracellular proteins is a dynamic process that in several cases competes with and acts as a reciprocal modification system to phosphorylation. O-Linked beta-N-acetylglucosamine transferase (OGT) levels are highest in the brain, and neurodegenerative disorders such as Alzheimer disease have been shown to involve abnormally phosphorylated ... [more]
Throughput
- Low Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
OGT ATXN10 | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - | |
ATXN10 OGT | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - |
Curated By
- BioGRID