BAIT
CREM
ICER, ICERI
cAMP responsive element modulator
GO Process (7)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- circadian regulation of gene expression [IMP]
- glycosphingolipid metabolic process [IMP]
- negative regulation of transcription, DNA-templated [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IGI]
- regulation of transcription, DNA-templated [ISO]
- response to cAMP [IDA]
- spermatogenesis [IMP, TAS]
Gene Ontology Molecular Function
Mus musculus
PREY
XPO1
AA420417, Crm1, Exp1, RP23-305E10.1
exportin 1, CRM1 homolog (yeast)
GO Process (8)
GO Function (4)
GO Component (11)
Gene Ontology Biological Process
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- protein export from nucleus [IDA, IMP, ISO]
- protein localization to nucleus [IMP]
- regulation of centrosome duplication [IMP]
- regulation of protein catabolic process [IMP]
- regulation of protein export from nucleus [IMP]
- ribosomal large subunit export from nucleus [ISO]
- ribosomal small subunit export from nucleus [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Transcription factors, cAMP-responsive element modulator (CREM) and Tisp40, act in concert in postmeiotic transcriptional regulation.
We previously isolated 80 TISP (transcript induced in spermiogenesis) genes whose transcription is dramatically induced during spermiogenesis. Our analysis here of the expression of these genes in the testis of the cAMP-responsive element modulator (CREM)-null mouse revealed that 54 TISP genes are under the transcriptional regulation of CREM. One CREM-regulated gene is TISP40, which encodes a basic leucine zipper (bZip)-type ... [more]
J. Biol. Chem. Jun. 02, 2006; 281(22);15073-81 [Pubmed: 16595651]
Throughput
- Low Throughput
Additional Notes
- Tisp40alpha interaction
Curated By
- BioGRID