BAIT

FEZ2

HUM3CL
fasciculation and elongation protein zeta 2 (zygin II)
GO Process (3)
GO Function (1)
GO Component (0)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Homo sapiens
PREY

C16ORF59

chromosome 16 open reading frame 59
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

FEZ1 dimerization and interaction with transcription regulatory proteins involves its coiled-coil region.

Assmann EM, Alborghetti MR, Camargo ME, Kobarg J

The fasciculation and elongation protein zeta1 (FEZ1) is a mammalian orthologue of the Caenorhabditis elegans protein UNC-76, which is necessary for axon growth in that nematode. In previous studies FEZ1 has been found to interact with protein kinase Czeta, DISC1, the agnoprotein of the human polyomavirus JC virus, and E4B, a U-box-type ubiquitin-protein isopeptide ligase. We reported previously that FEZ1 ... [more]

J. Biol. Chem. Apr. 14, 2006; 281(15);9869-81 [Pubmed: 16484223]

Throughput

  • Low Throughput

Curated By

  • BioGRID