OXA1L
Gene Ontology Biological Process
- aerobic respiration [IMP, NAS]
- mitochondrial proton-transporting ATP synthase complex assembly [IMP]
- mitochondrial respiratory chain complex I assembly [IMP]
- mitochondrial respiratory chain complex I biogenesis [IMP]
- negative regulation of ATPase activity [IMP]
- negative regulation of oxidoreductase activity [IMP]
- oxidation-reduction process [NAS]
- protein complex assembly [NAS]
- protein tetramerization [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
MRPL20
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Reconstituted Complex
An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.
Publication
Properties of the C-terminal tail of human mitochondrial inner membrane protein Oxa1L and its interactions with mammalian mitochondrial ribosomes.
In humans the mitochondrial inner membrane protein Oxa1L is involved in the biogenesis of membrane proteins and facilitates the insertion of both mitochondrial- and nuclear-encoded proteins from the mitochondrial matrix into the inner membrane. The C-terminal approximately 100-amino acid tail of Oxa1L (Oxa1L-CTT) binds to mitochondrial ribosomes and plays a role in the co-translational insertion of mitochondria-synthesized proteins into the ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID