BAIT

BIRC5.1-A

BIR1, Su2, XBIR1, XSurvivin1, Xsvv1, api4, bir1-A, epr-1, svv1, xSurvivin, xsurv
baculoviral IAP repeat-containing 5, gene 1
GO Process (0)
GO Function (0)
GO Component (0)
Xenopus laevis
PREY

INCENP-A

xl-incenp
inner centromere protein antigens 135/155kDa
GO Process (0)
GO Function (0)
GO Component (0)
Xenopus laevis

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Publication

Chromosome alignment and segregation regulated by ubiquitination of survivin.

Vong QP, Cao K, Li HY, Iglesias PA, Zheng Y

Proper chromosome segregation requires the attachment of sister kinetochores to microtubules from opposite spindle poles to form bi-oriented chromosomes on the metaphase spindle. The chromosome passenger complex containing Survivin and the kinase Aurora B regulates this process from the centromeres. We report that a de-ubiquitinating enzyme, hFAM, regulates chromosome alignment and segregation by controlling both the dynamic association of Survivin ... [more]

Science Dec. 02, 2005; 310(5753);1499-504 [Pubmed: 16322459]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
INCENP-A BIRC5.1-A
Affinity Capture-Western
Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Low-BioGRID
-

Curated By

  • BioGRID