Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Biochemical characterization of androgen receptor-interacting protein 4.

Domanskyi A, Virtanen KT, Palvimo JJ, Jaenne OA

ARIP4 [AR (androgen receptor)-interacting protein 4] is a member of the SNF2-like family of proteins. Its sequence similarity to known proteins is restricted to the centrally located SNF2 ATPase domain. ARIP4 is an active ATPase, and dsDNA (double-stranded DNA) and ssDNA (single-stranded DNA) enhance its catalytic activity. We show in the present study that ARIP4 interacts with AR and binds ... [more]

Biochem. J. Feb. 01, 2006; 393(0);789-95 [Pubmed: 16212558]

Throughput

  • Low Throughput

Curated By

  • BioGRID