BAIT
ITS3
SPAC19G12.14
1-phosphatidylinositol-4-phosphate 5-kinase Its3
GO Process (4)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
PREY
FOR3
SPCC895.05
formin For3
GO Process (9)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
- actin filament bundle assembly [IMP]
- actin filament organization [IMP]
- actin nucleation [ISM]
- activation of bipolar cell growth [IMP]
- establishment or maintenance of cell polarity regulating cell shape [IMP]
- microtubule cytoskeleton organization [IGI]
- mitotic actomyosin contractile ring assembly [IGI]
- protein localization to actin cytoskeleton [IMP]
- regulation of filamentous growth [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
Synthetic Lethality
A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.
Publication
Actin cables and the exocyst form two independent morphogenesis pathways in the fission yeast.
Cell morphogenesis depends on polarized exocytosis. One widely held model posits that long-range transport and exocyst-dependent tethering of exocytic vesicles at the plasma membrane sequentially drive this process. Here, we describe that disruption of either actin-based long-range transport and microtubules or the exocyst did not abolish polarized growth in rod-shaped fission yeast cells. However, disruption of both actin cables and ... [more]
Unknown Dec. 09, 2010; 0(0); [Pubmed: 21148300]
Throughput
- Low Throughput
Ontology Terms
- phenotype: inviable (APO:0000112)
Curated By
- BioGRID