BAIT

SRRM1

160-KD, POP101, SRM160
serine/arginine repetitive matrix 1
Homo sapiens
PREY

ZC3H14

MSUT-2, NY-REN-37, SUT2, UKp68
zinc finger CCCH-type containing 14
Alzheimer's Disease Project
GO Process (0)
GO Function (2)
GO Component (4)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin.

McCracken S, Longman D, Marcon E, Moens P, Downey M, Nickerson JA, Jessberger R, Wilde A, Caceres JF, Emili A, Blencowe BJ

In this study, we describe a rapid immunoaffinity purification procedure for gel-free tandem mass spectrometry-based analysis of endogenous protein complexes and apply it to the characterization of complexes containing the SRm160 (serine/arginine repeat-related nuclear matrix protein of 160 kDa) splicing coactivator. In addition to promoting splicing, SRm160 stimulates 3'-end processing via its N-terminal PWI nucleic acid-binding domain and is found ... [more]

J. Biol. Chem. Dec. 23, 2005; 280(51);42227-36 [Pubmed: 16159877]

Throughput

  • Low Throughput

Curated By

  • BioGRID