BAIT

ACTL6B

Actl6, ArpNa, Baf53b
actin-like 6B
GO Process (3)
GO Function (1)
GO Component (5)

Gene Ontology Molecular Function

Mus musculus

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Publication

Identification of a polymorphic, neuron-specific chromatin remodeling complex.

Olave I, Wang W, Xue Y, Kuo A, Crabtree GR

A variety of chromatin remodeling complexes are thought to assist sequence-specific transcription factors. The complexes described to date are expressed ubiquitously, suggesting that they have general transcriptional functions. We show that vertebrate neurons have a specialized chromatin remodeling complex, bBAF, specifically containing the actin-related protein, BAF53b, which is first expressed in postmitotic neurons at about murine embryonic day 12.5 (E12.5). ... [more]

Genes Dev. Oct. 01, 2002; 16(19);2509-17 [Pubmed: 12368262]

Throughput

  • Low Throughput

Curated By

  • BioGRID