BAIT
MYD88
myeloid differentiation primary response gene 88
GO Process (31)
GO Function (6)
GO Component (6)
Gene Ontology Biological Process
- 3'-UTR-mediated mRNA stabilization [ISO]
- JNK cascade [ISO]
- MyD88-dependent toll-like receptor signaling pathway [IGI, IMP]
- Toll signaling pathway [ISO]
- cell surface receptor signaling pathway [IMP]
- cytokine-mediated signaling pathway [ISO]
- defense response to Gram-positive bacterium [IMP]
- establishment of endothelial intestinal barrier [IMP]
- immune response [TAS]
- immunoglobulin mediated immune response [IMP]
- lipopolysaccharide-mediated signaling pathway [IMP]
- negative regulation of growth of symbiont in host [IMP]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IGI, IMP]
- positive regulation of JNK cascade [IMP]
- positive regulation of NF-kappaB transcription factor activity [IGI, IMP]
- positive regulation of chemokine biosynthetic process [IGI]
- positive regulation of interleukin-17 production [IMP]
- positive regulation of interleukin-23 production [IMP]
- positive regulation of interleukin-6 production [IMP]
- positive regulation of lymphocyte proliferation [IMP]
- positive regulation of smooth muscle cell proliferation [ISO]
- positive regulation of tumor necrosis factor production [IGI, IMP]
- regulation of cell proliferation [IGI]
- regulation of inflammatory response [IMP]
- response to interleukin-1 [ISO]
- response to lipopolysaccharide [IGI, IMP]
- response to molecule of fungal origin [IMP]
- response to peptidoglycan [IMP]
- response to virus [IMP]
- transmembrane receptor protein serine/threonine kinase signaling pathway [TAS]
- type I interferon biosynthetic process [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PRPF31
1500019O16Rik, 2810404O06Rik, AW554706, PRP31, RP11
PRP31 pre-mRNA processing factor 31 homolog (yeast)
GO Process (2)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
In vivo dual-tagging proteomic approach in studying signaling pathways in immune response.
Up to date, few successes have been achieved to identify the signaling molecules directly from immune cells due to their low-abundance and dynamic nature. Here, we designed an in vivo dual-tagging quantitative approach that integrated epitope-tagging which allows single affinity purification of the natural complexes formed at real-time, and amino acid-coded mass tagging (AACT) that assists mass spectrometry-based quantitative measurement, ... [more]
J. Proteome Res. Jun. 15, 2005; 4(3);941-9 [Pubmed: 15952741]
Throughput
- High Throughput
Curated By
- BioGRID