HDAC5
Gene Ontology Biological Process
- B cell activation [TAS]
- B cell differentiation [TAS]
- Notch signaling pathway [TAS]
- cellular response to insulin stimulus [NAS]
- chromatin modification [TAS]
- chromatin organization [TAS]
- chromatin remodeling [TAS]
- chromatin silencing [TAS]
- histone deacetylation [IDA]
- inflammatory response [TAS]
- negative regulation of cell migration involved in sprouting angiogenesis [IMP]
- negative regulation of myotube differentiation [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- negative regulation of transcription, DNA-templated [TAS]
- positive regulation of sequence-specific DNA binding transcription factor activity [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- regulation of gene expression, epigenetic [IMP]
- regulation of myotube differentiation [ISS]
- regulation of protein binding [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
YWHAE
Gene Ontology Biological Process
- cerebral cortex development [ISO]
- hippocampus development [ISO]
- negative regulation of peptidyl-serine dephosphorylation [ISO]
- negative regulation of protein dephosphorylation [ISO]
- negative regulation of protein serine/threonine kinase activity [TAS]
- neuron migration [ISO]
- protein targeting [ISO]
- regulation of membrane repolarization [ISO]
- regulation of potassium ion transmembrane transporter activity [ISO]
- signal transduction [TAS]
- substantia nigra development [ISO]
Gene Ontology Molecular Function- MHC class II protein complex binding [ISO]
- enzyme binding [IPI, ISO]
- histone deacetylase binding [ISO]
- ion channel binding [ISO]
- phosphoprotein binding [ISO]
- phosphoserine binding [ISO]
- poly(A) RNA binding [ISO]
- potassium channel regulator activity [ISO]
- protein binding [IPI]
- protein complex binding [IPI]
- protein domain specific binding [ISO]
- protein heterodimerization activity [ISO]
- protein kinase C inhibitor activity [TAS]
- MHC class II protein complex binding [ISO]
- enzyme binding [IPI, ISO]
- histone deacetylase binding [ISO]
- ion channel binding [ISO]
- phosphoprotein binding [ISO]
- phosphoserine binding [ISO]
- poly(A) RNA binding [ISO]
- potassium channel regulator activity [ISO]
- protein binding [IPI]
- protein complex binding [IPI]
- protein domain specific binding [ISO]
- protein heterodimerization activity [ISO]
- protein kinase C inhibitor activity [TAS]
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
The CRM1 nuclear export receptor controls pathological cardiac gene expression.
Diverse pathological insults trigger a cardiac remodeling process during which myocytes undergo hypertrophy, with consequent decline in cardiac function and eventual heart failure. Multiple transcriptional regulators of pathological cardiac hypertrophy are controlled at the level of subcellular distribution. For example, prohypertrophic transcription factors belonging to the nuclear factor of activated T cells (NFAT) and GATA families are subject to CRM1-dependent ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID