BAIT

ATF1

L000000138, YOR377W
Alcohol acetyltransferase; responsible for the major part of volatile acetate ester production during fermentation; main enzyme involved in terpenyl acetate synthesis; potential roles in lipid and sterol metabolism
GO Process (4)
GO Function (1)
GO Component (1)
Saccharomyces cerevisiae (S288c)
PREY

SLI1

YGR212W
N-acetyltransferase; confers resistance to the sphingolipid biosynthesis inhibitor myriocin (ISP-1) by converting it into N-acetyl-myriocin, co-operates with Ypk1p in mediating resistance to myriocin
GO Process (1)
GO Function (1)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Saccharomyces cerevisiae (S288c)

Phenotypic Suppression

A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.

Publication

Combinatorial gene overexpression and recessive mutant gene introduction in sake yeast.

Ano A, Suehiro D, Cha-Aim K, Aritomi K, Phonimdaeng P, Nontaso N, Hoshida H, Mizunuma M, Miyakawa T, Akada R

Industrial yeast strains are generally diploid and are often defective in sporulation. Such strains are hence thought to be less tractable for manipulation by genetic engineering. To facilitate more reliable genetic manipulation of the diploid yeast Japanese sake, we constructed variants of this strain that were homozygous for a URA3 deletion, homozygous for either MATa or MATalpha, and homozygous for ... [more]

Biosci. Biotechnol. Biochem. Mar. 23, 2009; 73(3);633-40 [Pubmed: 19270382]

Throughput

  • Low Throughput

Ontology Terms

  • chemical compound accumulation (APO:0000095)

Additional Notes

  • overexpression inhibits the overporoduction of isoamyl acetate caused by overproduction of ATF1

Curated By

  • BioGRID