Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

A functional interaction between RHA and Ubc9, an E2-like enzyme specific for Sumo-1.

Argasinska J, Zhou K, Donnelly RJ, Hay RT, Lee CG

RNA helicase A (RHA) is a member of the DEAH helicase family of proteins. Recent studies imply the role of RHA in the regulation of the topology of chromatin DNA, which could influence diverse nuclear processes such as transcription activity of the chromatin DNA and chromosome condensation. We previously reported that Ubc9, an E2-like enzyme specific for small ubiquitin-like modifier ... [more]

J. Mol. Biol. Jul. 30, 2004; 341(1);15-25 [Pubmed: 15312759]

Throughput

  • Low Throughput

Curated By

  • BioGRID