BAIT
HDAC3
HD3, RPD3, RPD3-2
histone deacetylase 3
GO Process (19)
GO Function (9)
GO Component (8)
Gene Ontology Biological Process
- Notch signaling pathway [TAS]
- cellular lipid metabolic process [TAS]
- cellular response to fluid shear stress [IDA]
- chromatin modification [TAS]
- negative regulation of JNK cascade [IMP]
- negative regulation of apoptotic process [TAS]
- negative regulation of cell cycle [TAS]
- negative regulation of myotube differentiation [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- negative regulation of transcription, DNA-templated [IMP]
- neurotrophin TRK receptor signaling pathway [TAS]
- positive regulation of TOR signaling [IMP]
- positive regulation of protein phosphorylation [IDA]
- positive regulation of transcription factor import into nucleus [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- protein deacetylation [IDA]
- regulation of protein stability [IDA]
- small molecule metabolic process [TAS]
- spindle assembly [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PHB2
BAP, BCAP37, Bap37, PNAS-141, REA, p22
prohibitin 2
GO Process (1)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Transcriptional regulation by the repressor of estrogen receptor activity via recruitment of histone deacetylases.
Histone acetyltransferases and deacetylases are recruited by transcription factors and adapter proteins to regulate specific subsets of target genes. We were interested in identifying interaction partners of histone deacetylase 1 (HDAC1) that might be involved in conferring target or substrate specificity. Using the yeast two-hybrid system, we isolated the repressor of estrogen receptor activity (REA) as a novel HDAC1-associated protein. ... [more]
J. Biol. Chem. Jun. 04, 2004; 279(23);24834-43 [Pubmed: 15140878]
Throughput
- Low Throughput
Curated By
- BioGRID